Uses
Lugol solution has been used in a study to assess narrow-band imaging without image magnification for detecting high-grade dysplasia and intramucosal esophageal squamous cell carcinoma. It has also been used in a study to determine its benefit in aiding detection of the presence and spread of small squamous cell carcinomas of the esophagus.
Definition
ChEBI: Iodine aqueous is an organic molecular entity.
General Description
Lugol solution is comprised of aqueous potassium iodide plus iodine.
Biological Activity
Iodine(I) interacts with Crystal Violet(CV) to form large CV-I complexes within the cytoplasm and outer layers of the cell.
Safety Profile
Experimental
reproductive effects. When heated to
decomposition it emits toxic fumes of I-.
Synthesis
With iodine 1.0g, potassium iodide 2.0g, distilled water 300.0mL.
Mix iodine and potassium iodide first, add a little distilled water and shake well, wait until completely dissolved, then add distilled water to 300mL.
