ST1481

Chemical Properties

Boiling point	780.6±70.0 °C(Predicted)
Density	1.37±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
pka	11.20±0.20(Predicted)
form	Solid
color	Light yellow to yellow
NCI Dictionary of Cancer Terms	gimatecan; ST1481
FDA UNII	7KKS9R192F
NCI Drug Dictionary	gimatecan

Product number	Packaging	Price	Product description	Buy
ChemScene CS-0006524	5mg	$350	Gimatecan 99.20%	Buy
American Custom Chemicals Corporation API0002825	1G	$1091.48	GIMATECAN 95.00%	Buy

Biological Activity

Gimatecan (ST1481) is a potent topoisomerase I inhibitor. It is an orally active camptothecin analog with antineoplastic activity.

in vivo

Gimatecan (2 mg/kg; treatment per os, every fourth day for four times) is effective for inhibiting tumor growth.

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target

Animal Model:	Athymic Swiss nude mice bearing HT1376 model
Dosage:	2 mg/kg
Administration:	Treatment per os, every fourth day for four times
Result:	Caused a marked tumor growth inhibition during treatment.

Topoisomerase I

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Shochem(Shanghai) Co.,Ltd	86-21-50800795	info@shochem.com	CHINA	288	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29810	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +8615988602810	sales@anbuchem.com	China	2998	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58

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