Description
Lactose Monohydrate is a highly purified pharmaceutical excipient obtained from milk as a by-product of the dairy sector. Being a disaccharide, each lactose molecule consists of one molecule of glucose and one molecule of galactose linked together via a β-1,4-glycoside bond.
Uses
Lactose monohydrate is commonly used as a food additive and filler for drug capsules.It’s also added to infant formulas, packaged snacks, frozen meals, and processed cookies, cakes, pastries, soups, and sauces, as well as several other foods.
Side effects
Individuals with severe lactose intolerance may wish to avoid or limit their intake of lactose monohydrate.
People with this condition don't produce enough of the enzyme that breaks down lactose in the intestines and may experience the following symptoms after consuming lactose:
bloating excessive burping gas stomach pain and cramps diarrhea While some have suggested that lactose-containing medications could cause unpleasant symptoms, research suggests that people with lactose intolerance can tolerate the small amounts of lactose monohydrate found in pills.
Incompatibilities
A Maillard-type condensation reaction is likely to occur between D-Lactose monohydrate and compounds with a primary amine group to form brown, or yellow-brown-colored products.The Maillard interaction has also been shown to occur between lactose and secondary amine. However, the reaction sequence stops with the formation of the imine, and no yellow-brown coloration develops.D-Lactose monohydrate is also incompatible with amino acids, amfetamines, and lisinopril.