Ly3502970

Uses

Orforglipron (LY3502970) (Compound 67) is an orally active agonist for Glucagon-like peptide-1 receptor (GLP-1R), which exhibits potency in ameliorates the type 2 diabete.

Mechanism of action

Ly3502970 is an incretin secreted from L cells of the small intestine when nutrients pass through the digestive tract, and glucose is transmitted via the GLP-1 receptor. Ly3502970 exhibits various actions such as dependent gastric emptying delay, and feeding suppression.