[S-(R*,S*)]-N-(3-Amino-2-hydroxy-4-phenylbutyroyl)-L-leucin
Bezeichnung:[S-(R*,S*)]-N-(3-Amino-2-hydroxy-4-phenylbutyroyl)-L-leucin
CAS-Nr58970-76-6
Englisch Name:Bestatin
CBNumberCB9324019
SummenformelC16H24N2O4
Molgewicht308.37
MOL-Datei58970-76-6.mol
Synonyma
[S-(R*,S*)]-N-(3-Amino-2-hydroxy-4-phenylbutyroyl)-L-leucin
[S-(R*,S*)]-N-(3-Amino-2-hydroxy-4-phenylbutyroyl)-L-leucin physikalisch-chemischer Eigenschaften
Schmelzpunkt | 245 °C (dec.)(lit.) |
alpha | D20 -15.5° (c = 1.0 in 1N HCl) |
Siedepunkt | 448.76°C (rough estimate) |
Dichte | 1.0917 (rough estimate) |
Brechungsindex | 1.5800 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
Löslichkeit | Aqueous Acid (Slightly, Sonicated), DMSO (Slightly, Heated) |
pka | 8.1, 3.1(at 25℃) |
Aggregatzustand | Powder |
Farbe | White |
Optische Aktivität | [α]20/D 11°, c = 1 in 1 M NaOH |
Wasserlöslichkeit | Soluble in water (<1 25), DMSO (2 mg/ml), methanol (5 mg/ml), 1eq. NaOH (50 mM), ethanol (<1 mg/ml at 25°C), acetic acid, aq. HCl, and alkaline solution. Insoluble in ethyl acetate, benzene, hexane, and chloroform. |
Merck | 13,9910 |
InChIKey | VGGGPCQERPFHOB-RDBSUJKOSA-N |
CAS Datenbank | 58970-76-6(CAS DataBase Reference) |
S-Sätze: | 22-24/25 |
WGK Germany | 3 |
RTECS-Nr. | OH2915000 |
HS Code | 29242998 |
Toxizität | LD50 in male, female mice, male, female rats (g/kg): 1.3, 1.9, 1.9, 2.1 s.c.; 0.19, 0.19, 0.90, 0.78 i.p.; >4.0, >4.0, >2.0, >2.0 orally (Sakakibara) |