3-Bromtoluol

Bezeichnung:3-Bromtoluol

CAS-Nr591-17-3

Englisch Name:3-Bromotoluene

CBNumberCB8437237

SummenformelC7H7Br

Molgewicht171.03

MOL-Datei591-17-3.mol

Synonyma

3-Bromtoluol

3-Bromtoluol physikalisch-chemischer Eigenschaften

Schmelzpunkt	-40 °C
Siedepunkt	183.7 °C(lit.)
Dichte	1.41 g/mL at 25 °C(lit.)
Dampfdruck	2.04 hPa ( 25 °C)
Brechungsindex	n20/D 1.552(lit.)
Flammpunkt	140 °F
storage temp.	Store below +30°C.
Löslichkeit	0.05g/l
Aggregatzustand	Liquid
Wichte	1.410
Farbe	Clear colorless to light yellow
Wasserlöslichkeit	insoluble
Merck	14,1439
BRN	1903633
Dielectric constant	5.3600000000000003
CAS Datenbank	591-17-3(CAS DataBase Reference)
NIST chemische Informationen	Benzene, 1-bromo-3-methyl-(591-17-3)
EPA chemische Informationen	m-Bromotoluene (591-17-3)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-36/37/38
S-Sätze:	26-36-37/39
RIDADR	UN 1993 3/PG 3
WGK Germany	3
RTECS-Nr.	XS7965400
F	8
Hazard Note	Harmful/Irritant
TSCA	Yes
HS Code	29036990
Giftige Stoffe Daten	591-17-3(Hazardous Substances Data)

Gefahreninformationscode (GHS)

3-Bromotoluene Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
colorless to light yellow liquid. Insoluble in water, soluble in ethanol and ether.
Verwenden
3-Bromotoluene was used in the precise determination of bromine isotope ratio in organic compounds by MC-ICPMS ( Multicollector-Inductively Coupled Plasma Mass Spectrometer). It undergoes palladium-catalyzed cyanation reaction in the presence of K4[Fe(CN)6] as the cyanide surrogate. It also undergoes palladium-catalyzed reaction with alkynyltriarylborates to yield trisubstituted alkenylboranes.
Application
3-Bromotoluene is used as a solvent (for fats, waxes or resins, and as a medium for carrying out reactions) and as a chemical intermediate.
synthetische
Synthesis of 3-Bromotoluene: It is derived from 3-bromo-4-aminotoluene by diazotization and reduction. The mixture of 95% ethanol, concentrated sulfuric acid and 3-bromo-4-aminotoluene was stirred and cooled to 10°C, and sodium nitrite solution was added to keep the reaction temperature not exceeding 10°C. After adding, continue stirring for 20min. Add the copper powder washed with ether, heat carefully, stop heating after the reaction starts, nitrogen will be released violently, and acetaldehyde will be formed. Then steam distillation is carried out until no oily substance evaporates. Separate the organic phase from the distillate and wash with 10% sodium hydroxide, water, concentrated sulfuric acid, and 5% sodium carbonate solution in sequence. Dry with anhydrous calcium chloride, filter, distill, collect 180-183 ℃ (99.75kPa) fractions to obtain colorless pure 3-bromotoluene with a yield of over 50%.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 1, p. 133, 1941
The Journal of Organic Chemistry, 57, p. 3772, 1992 DOI: 10.1021/jo00040a010
Allgemeine Beschreibung
3-Bromotoluene is an electron-rich aryl bromide. It participates in the Heck reaction. 3-Bromotoluene undergoes palladium-catalyzed cyanation reaction in the presence of K4[Fe(CN)6] as the cyanide surrogate. It undergoes palladium-catalysed reaction with alkynyltriarylborates to yield trisubstituted alkenylboranes.
Air & Water Reaktionen
Highly flammable. Insoluble in water.
Reaktivität anzeigen
3-Bromotoluene is incompatible with strong oxidizing agents.
Brandgefahr
3-Bromotoluene is combustible.

3-Bromotoluene Upstream-Materialien And Downstream Produkte

3-Bromtoluol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

591-17-3, 3-Bromotoluene Verwandte Suche:

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