3-β,14-Dihydroxy-5-β,14-β-card-20(22)-enolid
Bezeichnung:3-β,14-Dihydroxy-5-β,14-β-card-20(22)-enolid
CAS-Nr143-62-4
Englisch Name:DIGITOXIGENIN
CBNumberCB8187462
SummenformelC23H34O4
Molgewicht374.51
MOL-Datei143-62-4.mol
Synonyma
3-β,14-Dihydroxy-5-β,14-β-card-20(22)-enolid
3-β,14-Dihydroxy-5-β,14-β-card-20(22)-enolid physikalisch-chemischer Eigenschaften
| Schmelzpunkt | 253-255 °C (dec.)(lit.) |
| Siedepunkt | 423.5°C (rough estimate) |
| alpha | D17 +19.1° (c = 1.36 in methanol) |
| Dichte | 1.0284 (rough estimate) |
| Brechungsindex | 1.4433 (estimate) |
| storage temp. | Store at -20°C |
| Löslichkeit | DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml |
| Aggregatzustand | powder to crystal |
| pka | 14.93±0.70(Predicted) |
| Farbe | White to Almost white |
| Wasserlöslichkeit | 11.24mg/L(30 ºC) |
| Merck | 14,3162 |
| BRN | 95448 |
| Stabilität | Hygroscopic |
| LogP | 2.640 |
| CAS Datenbank | 143-62-4(CAS DataBase Reference) |
| Kennzeichnung gefährlicher | T |
| R-Sätze: | 25 |
| S-Sätze: | 45 |
| RIDADR | UN 3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS-Nr. | FH4975000 |
| HS Code | 2938.90.0000 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| Toxizität | cat,LDLo,intravenous,254ug/kg (0.254mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITING,Journal of the American Pharmaceutical Association. Vol. 27, Pg. 189, 1938. |
