3-Amino-4-hydroxybenzoesure

Bezeichnung:3-Amino-4-hydroxybenzoesure

CAS-Nr1571-72-8

Englisch Name:3-Amino-4-hydroxybenzoic acid

CBNumberCB8148119

SummenformelC7H7NO3

Molgewicht153.14

MOL-Datei1571-72-8.mol

Synonyma

3-Amino-4-hydroxybenzoesure

3-Amino-4-hydroxybenzoesure physikalisch-chemischer Eigenschaften

Schmelzpunkt	208 °C (dec.) (lit.)
Siedepunkt	276.03°C (rough estimate)
Dichte	1.3585 (rough estimate)
Brechungsindex	1.5500 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	Soluble in solvents.
pka	9.06±0.18(Predicted)
Aggregatzustand	Crystalline Powder
Farbe	Beige-gray to brown
Sensitive	Light Sensitive
maximale Wellenlänge (λmax)	308nm(H2O (pH 11))(lit.)
BRN	972238
InChI	InChI=1S/C7H7NO3/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,9H,8H2,(H,10,11)
InChIKey	MRBKRZAPGUCWOS-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=C(O)C(N)=C1
CAS Datenbank	1571-72-8(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-36/37/38
S-Sätze:	26-36
WGK Germany	3
Hazard Note	Irritant
HazardClass	IRRITANT, AIR SENSITIVE, LIGHT SENSITIVE
HS Code	29225090

Gefahreninformationscode (GHS)

3-Amino-4-hydroxybenzoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
beige-grey to brown crystalline powder
Application
3-Amino-4-hydroxybenzoic acid is the first matrix to be used specifically for carbohydrates. The other most commonly used matrices are α-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, and sinapinic acid. Matrix and sample solutions are mixed prior to laser exposure, spotted on a solid metallic surface, and allowed to dry before submitting them to MALDI. These matrices are characterized by high absorptivity of the laser radiation and the capability of forming fine crystalline solids during sample/matrix drying. In general, the more fine-grained and homogeneous the morphology of crystals formed with the analyte/matrix mixture, the more intense the MALDI mass spectrum of the analyte. 3-Amino-4-hydroxybenzoic acid produced [M+Na]+ ions from as little as 1 pmol of dextran hydrolysate and N-linked glycans released from glycoproteins.
Verwenden
3-Amino-4-hydroxybenzoic acid is used to produce 4-acetoxy-3-acetylamino-benzoic acid with acetic acid anhydride at temperature of 0 - 20°C. This reaction will need reagents aq. HCl and NaOAc.
Definition
ChEBI: A monohydroxybenzoic acid that is 4-hydroxybenzoic acid carrying an additional amino substitutent at position 3.
Synthesis Reference(s)
The Journal of Organic Chemistry, 54, p. 3740, 1989 DOI: 10.1021/jo00276a044

3-Amino-4-hydroxybenzoic acid Upstream-Materialien And Downstream Produkte

3-Amino-4-hydroxybenzoesure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1571-72-8, 3-Amino-4-hydroxybenzoic acid Verwandte Suche:

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