(+)-3-(3,4-Dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexan-3-carbonitril

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  Off-White Solid

• Verwenden

  Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells

• Definition

  ChEBI: A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby p tentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil.

(+)-3-(3,4-Dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexan-3-carbonitril Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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