Phenazopyridin

Bezeichnung:Phenazopyridin

CAS-Nr94-78-0

Englisch Name:3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE

CBNumberCB7770306

SummenformelC11H11N5

Molgewicht213.24

MOL-Datei94-78-0.mol

Synonyma

Phenazopyridin

Phenazopyridin physikalisch-chemischer Eigenschaften

Schmelzpunkt	136-137°
Siedepunkt	343.23°C (rough estimate)
Dichte	1.2597 (rough estimate)
Brechungsindex	1.6880 (estimate)
storage temp.	Amber Vial, -20°C Freezer, Under inert atmosphere
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Solid
pka	pKa 5.15(H2O,t =25) (Uncertain)
Farbe	Red crystals
Wasserlöslichkeit	904.20g/L(25 ºC)
BCS Class	2
Stabilität	Light Sensitive
InChIKey	QPFYXYFORQJZEC-FOCLMDBBSA-N
EPA chemische Informationen	Phenazopyridine (94-78-0)

Sicherheit

Giftige Stoffe Daten	94-78-0(Hazardous Substances Data)
Toxizität	LD50 ipr-rat: 560 mg/kg JPETAB 51,200,34

Gefahreninformationscode (GHS)

3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Phenazopyridine is a red crystalline compound. Slightly soluble in water.
Originator
Phenazopyridine ,AroKor Holdings Inc.
Verwenden
An azo dye used in treatment of urinary tract infections. 3-(Phenylazo)-2,6-pyridinediamine is used as an analgesic (urinary tract).
Verwenden
An azo dye used in treatment of urinary tract infections. Used as an analgesic (urinary tract).
Definition
ChEBI: A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorder ) and potential carcinogenicity.
Manufacturing Process
Phenyldiazene chloride reacted with 2,6-diaminopyridine and in the result 2,6diamino-3-(phenylazo)pyridine was obtained.
In practice it is usually used as monohydrochloride.
Trademarks
Pyridium (Parke-Davis);Azo gantrisin;Azodine;Phenazo;Pyridiate;Pyronium;Sedural.
Therapeutic Function
Urinary analgesic, Antiseptic, Diagnostic aid
Weltgesundheitsorganisation (WHO)
Phenazopyridine, an azo dye, was introduced in the 1950s as a urinary antiseptic. It was withdrawn in Greece in 1984 on grounds that it has a carcinogenic potential but it remains available in other countries, most frequently as a constituent of combination products.
Sicherheitsprofil
Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. Used as a local anesthetic. When heated to decomposition it emits toxic fumes of NOx.
Versand/Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Inkompatibilitäten
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE Upstream-Materialien And Downstream Produkte

Phenazopyridin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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