ETHYL 3,4-DIHYDROXYCINNAMATE

Bezeichnung:ETHYL 3,4-DIHYDROXYCINNAMATE

CAS-Nr66648-50-8

Englisch Name:ETHYL 3,4-DIHYDROXYCINNAMATE

CBNumberCB7713697

SummenformelC11H12O4

Molgewicht208.21

MOL-Datei66648-50-8.mol

ETHYL 3,4-DIHYDROXYCINNAMATE physikalisch-chemischer Eigenschaften

Schmelzpunkt	147～151℃
Siedepunkt	148-149 °C
Dichte	1.271±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	8.71±0.18(Predicted)
Aggregatzustand	Off-white to brown solid.
Farbe	White to off-white
Biologische Quelle	plant
LogP	2.418 (est)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	36/37/38-22
S-Sätze:	26-36

Gefahreninformationscode (GHS)

ETHYL 3,4-DIHYDROXYCINNAMATE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
Ethyl 3,4-dihydroxycinnamate shows anti-inflammatory, immunomodulatory, and anti-carcinogenic properties. It is a potent and specific inhibitor of NF-κB and its downstream inflammatory mediators: NOS2 (inducible nitric oxide synthase; NOS; NOS II), Cox-2 (cyclooxygenase-2), and prostaglandin E2 (PGE2). Ethyl 3,4-Dihydroxycinnamate prevents DNA single-strand breaks caused by H2O2.
Definition
ChEBI: Ethyl trans-caffeate is an ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol. It has a role as an anti-inflammatory agent and an antineoplastic agent. It is an alkyl caffeate ester and an ethyl ester. It is functionally related to a trans-caffeic acid.
Allgemeine Beschreibung
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biologische Aktivität
Ethyl dihydroxycinnamate exhibits potent cytotoxicity, inhibits COX-2 and P-hydroxybenzoic acid, both involved in inflammation and cytokine synthesis. It demonstrates antibacterial efficacy against MRSA and Bacillus subtilis and inhibits cancer cell growth, countering tumor formation.

ETHYL 3,4-DIHYDROXYCINNAMATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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