ATTAPULGITE

Bezeichnung:ATTAPULGITE

CAS-Nr12174-11-7

Englisch Name:ATTAPULGITE

CBNumberCB7382453

Summenformel2Al.3Mg.6O3Si

Molgewicht583.377

MOL-Datei12174-11-7.mol

Synonyma

Palygorskit

ATTAPULGITE physikalisch-chemischer Eigenschaften

Dichte	2.2 g/cm3
Farbe	White or gray monoclinic or orthorhombic crystals
Dielectric constant	1.8（Ambient）
Stabilität	Stable.
IARC	2B (Vol. 68) 1997, 3 (Vol. 68) 1997
EPA chemische Informationen	Attapulgite (12174-11-7)

Sicherheit

Giftige Stoffe Daten	12174-11-7(Hazardous Substances Data)
Toxizität	TCLo ihl-rat: 10 mg/m3/6H/13W-I:ETA BJIMAG 44,749,87

Gefahreninformationscode (GHS)

ATTAPULGITE Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
WEISSE BIS GRAUE FASERN.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: Krebserzeugend Kategorie 2; (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation.
INHALATIONSGEFAHREN
Verdampfung bei 20°C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim Dispergieren schnell erreicht werden.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Risiko der Lungenschädigung bei wiederholter oder längerer Faserexposition. Führt zu Fibrose. Möglicherweise krebserzeugend für den Menschen.
LECKAGE
Verschüttetes Material in abdichtbaren Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Persönliche Schutzausrüstung: Atemschutzgerät, P2-Filter für schädliche Partikel.
Chemische Eigenschaften
solid
Chemische Eigenschaften
Attapulgite occurs as a light cream colored, very fine powder. Particle size ranges depend on the grade and manufacturer.
Verwenden
Worldwide attapulgite production in 1983 was estimated at about 1.1 million tons, of which 84% came from the United States. The primary use of attapulgite is as an animal waste absorbent (cat litter). Other important uses of attapulgite in the United States are as a component of drilling muds, as oil and grease absorbents, and in fertilizer and pesticide formulations.
Verwenden
Excipient.
Vorbereitung Methode
Attapulgite occurs naturally as the mineral palygorskite.
Definition
A hydrated aluminum-magnesium silicate, the chief ingredient of fuller’s earth.
Hazard
Possible carcinogen.
Pharmazeutische Anwendungen
Attapulgite is widely used as an adsorbent in solid dosage forms. Colloidal clays (such as attapulgite) absorb considerable amounts of water to form gels and in concentrations of 2–5% w/v usually form oil-in-water emulsions. Activated attapulgite, which is attapulgite that has been carefully heated to increase its absorptive capacity, is used therapeutically as an adjunct in the management of diarrhea.
Sicherheitsprofil
Suspected carcinogen with experimental neoplastigenic and tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Sicherheit(Safety)
Attapulgite is widely used in pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material. It is not absorbed following oral administration. In oral preparations, activated attapulgite up to 9 g is used in daily divided doses as an adjunct in the management of diarrhea.
Lager
Attapulgite can adsorb water. It should be stored in an airtight container in a cool, dry, location.
Inkompatibilitäten
Attapulgite may decrease the bioavailability of some drugs such as loperamide and riboflavin. Oxidation of hydrocortisone is increased in the presence of attapulgite.
Regulatory Status
Included in nonparenteral medicines licensed in a number of countries worldwide including the UK and USA.

ATTAPULGITE Upstream-Materialien And Downstream Produkte

ATTAPULGITE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

12174-11-7, ATTAPULGITE Verwandte Suche:

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