2'-Deoxyadenosine Struktur

2'-Desoxyadenosin

Bezeichnung:2'-Desoxyadenosin

CAS-Nr958-09-8

Englisch Name:2'-Deoxyadenosine

CBNumberCB7162318

SummenformelC10H13N5O3

Molgewicht251.24

MOL-Datei958-09-8.mol

Synonyma

2'-Desoxyadenosin

2'-Desoxyadenosin physikalisch-chemischer Eigenschaften

Schmelzpunkt	187-189 °C
Siedepunkt	394.4°C (rough estimate)
Dichte	1.2938 (rough estimate)
Brechungsindex	1.7610 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
Löslichkeit	DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka	pK1:3.8(+1) (25°C,μ=0.1)
Aggregatzustand	powder
Farbe	White
Wasserlöslichkeit	Soluble in water and caustic soda.
Stabilität	Hygroscopic
InChI	InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
InChIKey	OLXZPDWKRNYJJZ-RRKCRQDMSA-N
SMILES	OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)C[C@@H]1O
CAS Datenbank	958-09-8(CAS DataBase Reference)
NIST chemische Informationen	Deoxyadenosine(958-09-8)
EPA chemische Informationen	Adenosine, 2'-deoxy- (958-09-8)

Sicherheit

RIDADR	2811
WGK Germany	3
RTECS-Nr.	AU7358600
F	10-23
TSCA	Yes
HazardClass	6.1
PackingGroup	Ⅲ
HS Code	2934999090

Gefahreninformationscode (GHS)

2'-Deoxyadenosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
2'-Deoxyadenosine is a natural deoxyribonucleoside, which is a structural fragment of deoxyribonucleic acid DNA. It is a purine nucleoside component of DNA comprised of adenosine linked by its N9 nitrogen to the C1 carbon of deoxyribose. Like other natural nucleosides, it is involved in the transmission of genetic information in almost all biological cells, affecting protein synthesis and polysaccharide. It plays a very important role in regulating the growth, proliferation, differentiation and inhibition of cells in vivo.
Verwenden
2'-Deoxyadenosine is used in paradoxical stimulation study of human sperm motility. It plays an essential role as sperm motility stimulants used in sperm micro-injection on mouse and human embryo development. It finds an application in some cells as an energy source under energy stress conditions. It is involved in various biological processes to compare the functions of adenosine analogues.
Definition
ChEBI: 2'-deoxyadenosine is a purine 2'-deoxyribonucleoside having adenine as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2'-deoxy-D-ribonucleoside and a purine 2'-deoxyribonucleoside.
synthetische
2'-deoxyadenosine synthesis: esterification of adenosine, acylation of an acylating agent and an acid binding agent to obtain an acylate; the obtained acylate is then subjected to reduction and purification to obtain 2'-deoxyadenosine. The esterification agent used in the esterification process is dialkyl tin oxide, 2'-O-p-toluenesulfonyladenosine is synthesized from adenosine, and 2'-deoxyadenosine is synthesized from 2'-O-p-toluenesulfonyladenosine glycosides.
Biologische Funktion
2'-Deoxyadenosine (Deoxyadenosine) is a critical component of DNA. When present in sufficiently high levels, deoxyadensoine can act as an immunotoxin and a metabotoxin. An immunotoxin disrupts, limits the function, or destroys immune cells. A metabotoxin is an endogenous metabolite that causes adverse health effects at chronically high levels.
Biologische Aktivität
2'-Deoxyadenosine is a deoxyribonucleoside and an intermediate in the purine nucleotide degradation pathway. It is transported into cells via facilitated diffusion or formed within cells by degradation of S-adenosylhomocysteine or AMP and is removed from cells by purine metabolism or is converted into adenine nucleotides. 2'-Deoxyadenosine has been used in the characterization of DNA conformations and the synthesis of nucleoside analogs as antiviral agents.
Source
2'-Deoxyadenosine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). 2'-Deoxyadenosine is a natural product found in Streptomyces jiujiangensis, Fritillaria przewalskii, and other organisms with data available.

2'-Deoxyadenosine Upstream-Materialien And Downstream Produkte

2'-Desoxyadenosin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

958-09-8, 2'-Deoxyadenosine Verwandte Suche:

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