Tildipirosin

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H301：Giftig bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H360：Kann die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen.

  H372：Schädigt bei Hautkontakt und Verschlucken die Organe bei längerer oder wiederholter Exposition.

• Sicherheit

  P201：Vor Gebrauch besondere Anweisungen einholen.

  P202：Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.

  P260：Dampf/Aerosol/Nebel nicht einatmen.

  P264：Nach Gebrauch gründlich waschen.

  P264：Nach Gebrauch gründlich waschen.

  P270：Bei Gebrauch nicht essen, trinken oder rauchen.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P302+P352：BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

  P308+P313：BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

  P332+P313：Bei Hautreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

  P337+P313：Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

  P405：Unter Verschluss aufbewahren.

Tildipirosin Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Tildiprosin is an antibiotic derived from a tylosin derivative by iodination and reaction with piperidine. Tildiprosin provides good protection against Bartonella henselae in livestock. Treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica and Haemophilus parasuis sensitive to tildipirosin. The introduction of a third basic moiety into the tylosin core provides a wider spectrum of antibiotic action than the dibasic analogues such as tilmicosin. Tildipirosin′s interaction with the ribosomal site of action differs from that of tylosin and tilmicosin.

• Verwenden

  Tildipirosin is a novel 16-membered-ring macrolide used in veterinary medicine. Tildipirosin treats bacterial pathogens including Mannheimia haemolytica and Pasteurella multocida that cause respiratory tract infections in cattle and swine (BRD Bovine Respiratory Disease).

• Verwenden

  Tildiprosin is a semi-synthetic antibiotic derived from a tylosin derivative by iodination and reaction with piperidine. The introduction of a third basic moiety into the tylosin core provides a wider spectrum of antibiotic action than the dibasic analogues such as tilmicosin, in particular good protection against Pasteurella in livestock. Tildipirosin’s interaction with the ribosomal site of action differs from that of tylosin and tilmicosin.

• Biochem/physiol Actions

  Tildipirosin has additionally proven effective against Histophilus somni, Bordetella bronchiseptica, Actinobacillus pleuropneumoniae, and Haemophilus parasuis, which can also be associated with animal respiratory diseases.

• Mechanism of action

  The mechanism of action of Tildipirosin consists of the inhibition of the bacterial protein synthesis as a consequence of binding to 23S ribosomal RNA for 50S subunit.

• Nebenwirkungen

  In target animal safety studies, administration of the maximum recommended injection volume (5 ml) occasionally caused slight swellings at the injection site that were not painful on palpation. Swellings persisted for up to 3 days. Pathomorphological injection site reactions resolved completely within 21 days. During clinical trials, pain on injection and injection site swellings were seen very commonly in treated pigs. These swellings resolved within 1 to 6 days. During clinical trials, treatment caused shock symptoms in 2 out of 1048 animals. These symptoms quickly resolved in one animal, but led to death in the other animal.

Tildipirosin Upstream-Materialien And Downstream Produkte

Tildipirosin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(182)Suppliers

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