3-(6-Desoxy-alpha-L-mannopyranosy-loxy)-1,5,11a,14,19-pentahydroxy-card-20(22)-enolid Produkt Beschreibung

G-STROPHANTHIN Struktur
630-60-4
  • CAS-Nr.630-60-4
  • Bezeichnung:3-(6-Desoxy-alpha-L-mannopyranosy-loxy)-1,5,11a,14,19-pentahydroxy-card-20(22)-enolid
  • Englisch Name:G-STROPHANTHIN
  • Synonyma:3-(6-Desoxy-α-L-mannopyranosyloxy)-1,5,11a,14,19-pentahydroxycard-20(22)-enolid;3-(6-Desoxy-alpha-L-mannopyranosy-loxy)-1,5,11a,14,19-pentahydroxy-card-20(22)-enolid
    oubain;uabaina;uabanin;QUABAIN;OUABAIN;ouabaine;ASTROBAIN;GRATIBAIN;strodival;NSC 25485
  • CBNumber:CB6753829
  • Summenformel:C29H44O12
  • Molgewicht:584.65
  • MOL-Datei:630-60-4.mol
3-(6-Desoxy-alpha-L-mannopyranosy-loxy)-1,5,11a,14,19-pentahydroxy-card-20(22)-enolid physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :200°C
  • Siedepunkt: :561.69°C (rough estimate)
  • Dichte :1.1941 (rough estimate)
  • Brechungsindex :-32 ° (C=1, H2O)
  • storage temp.  :Desiccate at -20°C
  • Löslichkeit :H2O: 10 mg/mL cold
  • Aggregatzustand :powder
  • pka :13.04±0.70(Predicted)
  • Farbe :white
  • Wasserlöslichkeit :13g/L(25 ºC)
  • Merck  :6901
  • EPA chemische Informationen :Ouabain (630-60-4)
Sicherheit
  • Kennzeichnung gefährlicher :T
  • R-Sätze: :23/25-33
  • S-Sätze: :45
  • RIDADR  :UN 1544 6.1/PG 1
  • WGK Germany  :3
  • RTECS-Nr. :RN3850000
  • F  :8
  • Toxizität :LD50 oral in guinea pig: 8280ug/kg

G-STROPHANTHIN Chemische Eigenschaften,Einsatz,Produktion Methoden

  • R-Sätze Betriebsanweisung: R23/25:Giftig beim Einatmen und Verschlucken.
    R33:Gefahr kumulativer Wirkungen.
  • S-Sätze Betriebsanweisung: S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
  • Chemische Eigenschaften Ouabain is a white crystalline solid.
  • Allgemeine Beschreibung Odorless, white crystals or crystalline powder as an octahydrate. Used to produce rapid digitalization in acute congestive heart failure. Also recommended in treatment of atrial or nodal paroxysmal tachycardia and atrial flutter.
  • Reaktivität anzeigen When heated to decomposition, G-STROPHANTHIN emits acrid smoke and fumes. Hydrolysis yields one mole ouabagenin and one mole rhamnose. Stable in air, but affected by light (G-STROPHANTHIN octahydrate) [EPA, 1998].
  • Health Hazard G-STROPHANTHIN is classified as extremely toxic. Probable oral lethal dose in humans is less than 5 mg/kg or a taste (less than 7 drops) for 70 kg (150-lb.) person. Exposure may result in respiratory and cardiac failure, and/or hyperalkemia. Patients with frequent premature ventricular heart beats or who have received any preparation of digitalis during preceding three weeks are prone to toxicity.
  • Brandgefahr When heated to decomposition, G-STROPHANTHIN emits acrid smoke and fumes. Hydrolysis yields one mole ouabagenin and one mole rhamnose. Stable in air, but affected by light (G-STROPHANTHIN octahydrate)
  • Biologische Aktivität Selective Na + , K + -ATPase inhibitor.
  • Sicherheitsprofil Poison by ingestion, intramuscular, intraperitoneal, intravenous, subcutaneous, and parented routes. Moderately toxic by intraduodenal route. A cardac stimulant. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes
  • mögliche Exposition Ouabain, similar to digitoxin, is used to produce rapid digitalization in acute congestive heart failure. Also recommended in treatment of atrial or nodal paroxysmal tachycardia and atrial flutter; enzyme inhibitor.
  • Versand/Shipping UN1544 Alkaloids, solid, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
  • läuterung methode It crystallises from water as the octahydrate. Dry it at 130o. It decomposes at 190o when dry. Store it in the dark as it is light sensitive, but it is stable in air. Its solubility (g/100mL) in H2O is 1.3 (~25o), 20 (~100o), and in EtOH it is 1.0 (~25o) and 12.5 (~78o). It is highly TOXIC as it is an inhibitor of cation transport and of Na+ and K+ ATPase. [Beilstein 18/5 V 625.]
  • Inkompatibilitäten Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.).
G-STROPHANTHIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-(6-Desoxy-alpha-L-mannopyranosy-loxy)-1,5,11a,14,19-pentahydroxy-card-20(22)-enolid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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630-60-4, G-STROPHANTHIN Verwandte Suche:
  • (1beta,3beta,5beta,11alpha)-ahydroxy
  • (1beta,3beta,5beta,11alpha)-hydroxy
  • 3-((6-deoxy-alpha-l-mannopyranosyl)oxy)-1,5,11alpha,14,19-pentahydroxycard-20(
  • 3-[(6-deoxy-.alpha.-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-,(1.beta.,3.beta.,5.beta.,11.aCard-20(22)-enolide
  • card-20(22)-enolide,3-((6-deoxy-alpha-l-mannopyranosyl)oxy)-1,5,11,14,19-penta
  • card-20(22)-enolide,3-[(6-deoxy-alpha-l-mannopyranosyl)oxy]-1,5,11,14,19-pent
  • g-strophicor
  • ouabagenin-l-rhamnosid
  • Strophanthin(quabain)
  • strophoperm
  • strophosan
  • uabaina
  • uabanin
  • 20(22),5BETA-CARDENOLID-1BETA,3BETA,5BETA,14BETA-HEXAL 3BETA-ALPHA-1-RHAMNOSIDE
  • 3-[(6-DEOXY-ALPHA-L-MANNOPYRANOSYL)OXY]-1,5,11A,14,19-PENTAHYDROXYCARD-20(22)-ENOLIDE
  • 3-[(6-DEOXY-ALPHA-L-MANNOPYRANOSYL)OXY]-1,5,11ALPHA-14,19-PENTAHYDROXYCARD-20(22)-ENOLIDE
  • ACOCANTHERIN
  • ACOCANTHERINE
  • ASTROBAIN
  • Diveasidum
  • GRATIBAIN
  • GRATUS STROPHANTHIN
  • G-STROPHANTHIN
  • GRATUS STROPHANTHIN 99%
  • Ouabain - anhydrous
  • QUABAIN
  • PUROSTROPHAN
  • STROPHANTHIN, G-
  • OUABAIN
  • ouabageninl-rhamnoside
  • ouabaine
  • oubain
  • rectobaina
  • solufantina
  • strodival
  • strophalen
  • GRATIBAIN 99%
  • 4-[(1R,3S,5S,10R,11R,13R,14S,17S)-1,5,11,14-tetrahydroxy-10-(hydroxyme thyl)-13-methyl-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-y l]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenant hren-17-yl]-5H-furan-2-one
  • Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, (1β,3β,5β,11α)-
  • NSC 25485
  • Ouabain (8CI)
  • 3-[(6-deoxy-.alpha.-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, (1.beta.,3.beta.,5.beta.,11.aCard-20(22)-enolide
  • 1β,5,11α,14,19-Pentahydroxy-3β-(α-L-rhamnopyranosyloxy)-5β,14β-carda-20(22)-enolide
  • 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1β,5,11α,14,19-pentahydroxy-5β,14β-card-20(22)-enolide
  • 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1β,5,11α,14,19-pentahydroxy-5β-card-20(22)-enolide
  • 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11α,14,19-pentahydoxycard-20(22)-enolide
  • Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, hydrate (1:8), (1β,3β,5β,11α)-
  • 630-60-4
  • C29H44O12
  • Sugars
  • Rhamnose
  • Steroids
  • Glycosides
  • Steroidglycosides
  • Biochemistry
  • Glycosides
  • Rhamnose
  • Steroidglycosides