Chlorophacinon (ISO)

Bezeichnung:Chlorophacinon (ISO)

CAS-Nr3691-35-8

Englisch Name:Chlorophacinone

CBNumberCB6372862

SummenformelC23H15ClO3

Molgewicht374.82

MOL-Datei3691-35-8.mol

Synonyma

Chlorophacinon

Chlorophacinon (ISO)

Chlorophacinon (ISO) physikalisch-chemischer Eigenschaften

Schmelzpunkt	138°
Siedepunkt	490.38°C (rough estimate)
Dichte	1.1517 (rough estimate)
Brechungsindex	1.4585 (estimate)
Flammpunkt	>100 °C
storage temp.	-20°C
pka	2.61±0.10(Predicted)
Merck	13,2171
NIST chemische Informationen	Chlorophacinone(3691-35-8)
EPA chemische Informationen	Chlorophacinone (3691-35-8)

Sicherheit

Kennzeichnung gefährlicher	T+;N,N,T+
R-Sätze:	23-27/28-48/24/25-50/53
S-Sätze:	36/37-45-60-61
RIDADR	UN 2811
RTECS-Nr.	NK5335000
HazardClass	6.1(a)
PackingGroup	I
HS Code	29147000
Giftige Stoffe Daten	3691-35-8(Hazardous Substances Data)
Toxizität	LD50 oral in rabbit: 50mg/kg

Gefahreninformationscode (GHS)

Chlorophacinone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R23:Giftig beim Einatmen.
R27/28:Sehr giftig bei Berührung mit der Haut und beim Verschlucken.
R48/24/25:Giftig: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Berührung mit der Haut und durch Verschlucken.
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Chlorophacinone is produced by condensation of 1- phenyl-1-(4-chlorophenyl) acetone with dimethyl phthalate in the presence of sodium methoxide (31).
This compound was introduced in 1961 and is now widely used in Europe, the United States, and elsewhere. It is used in baits against norway rats at a concentration of 0.005–0.01%. Bait containing 0.025% chlorophacinone gave a complete kill of house mice after a 7-d feeding period but, in other tests, survivors were recorded following 10 and 21 days of feeding (5). Chlorophacinone acts as an uncoupler of oxidative phosphorylation as well as an anticoagulant (32), which is unusual among this group of compounds.
Chemische Eigenschaften
Chlorophacinone is a highly toxic crystalline solid.
Verwenden
Chlorophacinone (CPN) is an anticoagulant rodenticide widely used to control rodent infestations.
Verwenden
Anticoagulant rodenticide.
Definition
ChEBI: Chlorophacinone is a diarylmethane and a beta-triketone.
Allgemeine Beschreibung
Crystals. Commercially available as oil concentrate and as dust concentrate. Used as an anticoagulant rodenticide. Chronic acting, multiple dose rodenticide.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
Fire may produce irritating or poisonous gases.
Health Hazard
Chlorphacinon is highly toxic orally and by skin absorption. The probable oral lethal dose for humans is less than 5 mg/kg to 50 mg/kg, or between a taste (less than 7 drops) and 1 teaspoonful for a 150 lb. (70 kg) person.
Health Hazard
Highly toxic anticoagulant rodenticide; lowchlorine content but highly toxic; exhibitsacute, delayed, and chronic poisoning;symptoms include bleeding of nose andgum, blood in cough, urine, and stool,abdominal pain and hemorrhage; can beabsorbed through skin causing systemicpoisoning; ingestion of 1–2 g is estimatedto be fatal dose for adult human; U.S. EPAlisted extremely hazardous substance.
LD50 oral (rat): ～2 mg/kg
LD50 oral (mouse): ～1 mg/kg
LD50 oral (rabbit): 50 mg/kg
LD50 skin (rabbit): 200 mg/kg.
Brandgefahr
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Fire may produce irriating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated Chlorphacinon emits toxic fumes of chlorides.
Landwirtschaftliche Anwendung
Rodenticide: This material is an anticoagulant rodenticide used around livestock and also on crops such as artichokes. Some brands are labeled for use indoors and outdoors for the control of mice, rats, moles, muskrats, voles and vampire bats. Not approved for use in EU countries. Registered for use in the U.S. There are 24 global suppliers.
Handelsname
AFNOR®; CAID®; DELTA®; DRAT RAT BAIT®; ENDORATS®; LIPHADIONE®; LM 91®; MICROZUL®; MURIOL®; PARTOX®[C]; QUICK®; RAMUCIDE®; RANAC®; RATOMET®; RAVIAC®; ROZOL®[C]; TOPITOX®
Sicherheitsprofil
Poison by ingestion and skin contact. Human systemic effects by ingestion: vascular changes. A pesticide. When heated to decomposition it emits toxic fumes of Cl-.
mögliche Exposition
Agricultural Chemical. This material is an anticoagulant rodenticide. A potential danger to those involved in its manufacture, formulation, and application are at risk.
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 minutes, occasionally lifting upper and lower lids. Seekmedical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
Lager
Color Code—Green: General storage may be used.Prior to working with this chemical you should be trainedon its proper handling and storage. Store in tightly closedcontainers in a cool, well-ventilated area.
Versand/Shipping
UN3027 Coumarin derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Waste disposal
Incineration at high temperature with effluent gas scrubbing.

Chlorophacinone Upstream-Materialien And Downstream Produkte

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