Benzoesure, 2-Hydroxy-5-sulfo-, Verbindung mit [4S-(4α,4aα,5α,5aα,12aα)]-7-Chlor-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylen-1,11-dioxo-2-naphthacencarboxamid (1:1)

MECLOCYCLINE SULFOSALICYLATE SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Antibacterial;Antibacterial

• Verwenden

  Meclocycline Sulfosalicylate Salt is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in solution with 2-hydroxy-3-carboxybenenesulphonic acid. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. The unusual complex counter-ion is likely to add an antiseptic component to the use of the compound for skin infections.

• Verwenden

  Meclocycline is a tetracycline antibiotic that is topically used for skin infections and irritations.

• Trademarks

  Meclan (Johnson & Johnson).

• Allgemeine Beschreibung

  Meclocycline, 7-chloro-6-deoxy-6-demethyl-6-methylene-5-oxytetracycline sulfosalicylate (Meclan), is a semisyntheticderivative prepared from oxytetracycline.Although meclocycline has been used in Europe for manyyears, it became available only relatively recently in theUnited States for a single therapeutic indication, the treatmentof acne. It is available as the sulfosalicylate salt in a1% cream.
  Meclocycline sulfosalicylate is a bright yellow, crystallinepowder that is slightly soluble in water and insolublein organic solvents. It is light sensitive and should be storedin light-resistant containers.

Benzoesure, 2-Hydroxy-5-sulfo-, Verbindung mit [4S-(4α,4aα,5α,5aα,12aα)]-7-Chlor-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylen-1,11-dioxo-2-naphthacencarboxamid (1:1) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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