Procaterol

(R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Like pirbuterol, procaterol exhibits similar broncholytic properties as albuteral, but it has somewhat of a more prolonged action. It is recommended for use as an inhaled drug for treating bronchial asthma.

• Chemische Eigenschaften

  Off-White Solid

• Verwenden

  A labelled intermediate of the enantiomer of Florfenicol (F405750), an antibacterial agent.

• Definition

  ChEBI: 8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one is a member of quinolines.

• Trademarks

  Pro-Air (Parke-Davis).

• Synthese

  Procaterol, 5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-8-hydroxy-2-(1H) quinolone (23.3.25), is synthesized by acylation of 8-hydroxy-2(1H)-quinolone with 2-bromobutyric acid chloride at the fifth position of the quinoline system, which gives the compound 23.3.23. This undergoes action of isopropylamine, forming an aminoketone 23.3.24, the carbonyl group of which is reduced by sodium borohydride, giving procaterol (23.3.25) .

  

Procaterol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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