Iopydol

iopydol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Hytrast Vial,Guerbet

• Verwenden

  Iopydol is the X-ray contrast reagent.

• Verwenden

  Diagnostic aid (radiopaque medium, bronchographic) .

• Definition

  ChEBI: Iopydol is a chloropyridine.

• Manufacturing Process

  50 g 4-pyridone was dissolved in 300 ml 20% hydrochloric acid and slowly mixed with 180 g of chloroiodide in 200 ml 20% hydrochloric acid. Then the obtained dark solution was strong alkalized with sodium hydroxide. The solvent was removed to dryness and sodium salt diiod-4-pyridone was
  obtained. It was dissolved in water, filtered and equivalent quantity of glacial acetic acid or hydrochloric acid was added to give 3,5-diiod-4-pyridone as a powder. 34.5 g 3,5-diiod-pyridone was dissolved in 100 ml 1 N NaOH by heating on a water bath and added to a 15 g of monochlorohydrine added. The mixture was heated on water bath before a dense pasty mass obtained. It was filtered off and treated with 1 N NaOH. The obtained 1-(2,3- dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone was recrystallized from diluted hydrochloric acid. MP: 161°C.

• Therapeutic Function

  Diagnostic aid

iopydol Upstream-Materialien And Downstream Produkte

Iopydol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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