(3R,3'S,5'R)-3,3'-Dihydroxy-β,K-carotin-6'-on

Bezeichnung:(3R,3'S,5'R)-3,3'-Dihydroxy-β,K-carotin-6'-on

CAS-Nr465-42-9

Englisch Name:CAPSANTHIN

CBNumberCB5380132

SummenformelC40H56O3

Molgewicht584.87

MOL-Datei465-42-9.mol

Synonyma

(3R,3'S,5'R)-3,3'-Dihydroxy-β,K-carotin-6'-on

(3R,3'S,5'R)-3,3'-Dihydroxy-β,K-carotin-6'-on physikalisch-chemischer Eigenschaften

Schmelzpunkt	177-178℃
alpha	Cd +36° (chloroform)
Siedepunkt	581.82°C (rough estimate)
Dichte	1.012
Brechungsindex	1.4960 (estimate)
storage temp.	-20°C
Löslichkeit	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
Aggregatzustand	Solid
pka	14.85±0.60(Predicted)
Farbe	Dark Red to Very Dark Brown
Optische Aktivität	〔α〕Cd +36 (CHCl3)
maximale Wellenlänge (λmax)	λ: 467-471 nm Amax
Merck	14,1769
Stabilität	Light Sensitive, Temperature Sensitive
LogP	9.467 (est)

Sicherheit

WGK Germany	3
HS Code	2914.50.3000
Giftige Stoffe Daten	465-42-9(Hazardous Substances Data)

CAPSANTHIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Capsanthin is a carotenoid that has been found in C. annuum and has diverse biological activities. It reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and phosphorylation of ERK and p38 and prevents hydrogen peroxide-induced inhibition of gap junction intercellular communication in WB-F344 rat liver epithelial cells. Capsanthin (0.2 mg/animal) reduces the number of colonic aberrant crypt foci and preneoplastic lesions in a rat model of N-methylnitrosourea-induced colon carcinogenesis. It also reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate (TPA; ).
Verwenden
Capsanthin may be used as an analytical reference standard for the quantification of the analyte in red pepper powder, red pepper fruits, paprika and oleoresin using chromatography techniques.
Verwenden
antineoplastic
Definition
ChEBI: Capsanthin is a carotenone. It has a role as a plant metabolite.
Allgemeine Beschreibung
Capsanthin, also known as the red pepper carotenoid, is one of the major color pigments of paprika oleoresin, an oil-soluble extract, isolated from the fruits of Capsicum annum Linn or Capsicum frutescens. It is widely used as a color additive in food industries across the globe. The photoprotective effect of capsanthin protects human dermal fibroblasts against UVB induced DNA damage.
Hazard
A poison by skin contact.
Biochem/physiol Actions
Capsanthin is a potential nutraceutical, is found in green vegetables and is a constituent of paprika and asparagus. Capsanthin has been shown to exhibit anti-proliferative function.
Sicherheitsprofil
A poison by skin contact. When heated to decomposition it emits acrid smoke and irritating vapors.
läuterung methode
Possible impurities are zeaxanthin and capsorubin (below). Purify capsanthin by chromatography on a column of alumina (grade IV) and develop with 0.2% EtOH in *C6H6. It

CAPSANTHIN Upstream-Materialien And Downstream Produkte

(3R,3'S,5'R)-3,3'-Dihydroxy-β,K-carotin-6'-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

465-42-9, CAPSANTHIN Verwandte Suche:

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