Methyl-4-methoxy-3-oxobutyrat

Bezeichnung:Methyl-4-methoxy-3-oxobutyrat

CAS-Nr41051-15-4

Englisch Name:Methyl 4-methoxyacetoacetate

CBNumberCB5291234

SummenformelC6H10O4

Molgewicht146.14

MOL-Datei41051-15-4.mol

Synonyma

Methyl-4-methoxy-3-oxobutyrat

Methyl-4-methoxy-3-oxobutyrat physikalisch-chemischer Eigenschaften

Schmelzpunkt	-80℃
Siedepunkt	89 °C/8.5 mmHg (lit.)
Dichte	1.129 g/mL at 25 °C (lit.)
Brechungsindex	n20/D 1.431(lit.)
Flammpunkt	193 °F
storage temp.	Sealed in dry,Room Temperature
Aggregatzustand	clear liquid
pka	9.88±0.46(Predicted)
Wichte	1.129
Farbe	Colorless to Light yellow to Light orange
BRN	1761215
InChIKey	QGBPKJFJAVDUNC-UHFFFAOYSA-N
LogP	0.340 (est)
CAS Datenbank	41051-15-4(CAS DataBase Reference)
NIST chemische Informationen	Methyl 4-methoxyacetoacetate(41051-15-4)
EPA chemische Informationen	Methyl 4-methoxyacetoacetate (41051-15-4)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
F	10
HS Code	29189900

Gefahreninformationscode (GHS)

Methyl 4-methoxyacetoacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
colorless to yellow liquid
Verwenden
Methyl 4-methoxyacetoacetate has been used in generation of a small focused library of diversely functionalized dihydropyrimidine derivatives via one-pot three-component Biginelli cyclocondensation of β-ketoesters, aldehydes and (thio)ureas.
Verwenden
Methyl 4-Methoxyacetoacetate is a reactant in the formation of an abiotic poorphyrinogen in aqueous solution.
synthetische
The preparation method of a 4-methoxyl group methyl acetoacetate: add solvents tetrahydrofurane in a kettle. and pass into rare gas element, the temperature in the kettle arranging reactor is 15-25℃, industrial sodium hydride and metal alkaline compound is added under whipped state, add solvents tetrahydrofurane again, the mixed solution reaction 4-6h of methyl alcohol and 4-chloro methyl acetoacetate is dripped in less than 20℃, then be warming up to 20-25℃ and continue reaction 4-15h, TLC detection reaction is complete, reduce system temperature to 6-10℃, add the hydrochloric acid soln regulation system pH=5-7 that volumetric molar concentration is 2mol/L, stratification, after separatory, upper strata is concentrated is spin-dried for removing solvents tetrahydrofurane, then colorless product 4-methoxyl group methyl acetoacetate is obtained by wiped film molecular distillation.

Methyl 4-methoxyacetoacetate Upstream-Materialien And Downstream Produkte

Methyl-4-methoxy-3-oxobutyrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

41051-15-4, Methyl 4-methoxyacetoacetate Verwandte Suche:

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