4-Hydroxybenzylamine Struktur

4-Hydroxybenzylamine

Bezeichnung:4-Hydroxybenzylamine

CAS-Nr696-60-6

Englisch Name:4-Hydroxybenzylamine

CBNumberCB5207547

SummenformelC7H9NO

Molgewicht123.15

MOL-Datei696-60-6.mol

4-Hydroxybenzylamine physikalisch-chemischer Eigenschaften

Schmelzpunkt	123-128 °C
Siedepunkt	262.4±15.0 °C(Predicted)
Dichte	1.141±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
Löslichkeit	DMSO (Slightly), Water (Slightly, Heated)
Aggregatzustand	Powder
pka	8.93±0.26(Predicted)
Farbe	Off-white to pale yellow
InChIKey	RQJDUEKERVZLLU-UHFFFAOYSA-N
LogP	0.350 (est)
CAS Datenbank	696-60-6(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	34-36/37/38
S-Sätze:	26-36/37/39-24/25
RIDADR	2735
WGK Germany	3
Hazard Note	Irritant
HazardClass	IRRITANT, CORROSIVE
HS Code	29214990

Gefahreninformationscode (GHS)

4-Hydroxybenzylamine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
4-HOBA is an isomer of the isoketal scavenger 2-HOBA that has reduced efficacy as an isoketal scavenger. Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II in mice. 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension.
Chemische Eigenschaften
4-Hydroxybenzylamine, also known as tyramine and p-hydroxyphenethylamine, is a white or off-white or light green solid. Tyramine, a compound originally isolated from ergot alkaloids and decomposed animal tissues, is an important synthetic drug intermediate.
Verwenden
4-Hydroxybenzylamine (cas# 696-60-6) is a compound useful in organic synthesis.
synthetische
Synthesis of 4-Hydroxybenzylamine:Ammonia is passed into 500 ml of ethanol at 10° C. until saturation is reached, 122.1 g=1 mole of p-hydroxybenzaldehyde, 20 g of Raney nickel and 0.1 ml of concentrated sulfuric acid are added and the mixture is stirred in an autoclave for 6 hours at room temperature and under a hydrogen pressure of 100 atmospheres. After releasing the pressure, the catalyst is filtered off and the filtrate is boiled up with active charcoal, filtered and concentrated. The residue is recrystallized from a mixture of ethanol and ether. This gives 104 g (85% of theory), melting point: 104° C.
Literature source US04391805
Definition
ChEBI: 4-Hydroxybenzylamine is an aromatic amine.
target
GABA Receptor

4-Hydroxybenzylamine Upstream-Materialien And Downstream Produkte

4-Hydroxybenzylamine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

696-60-6, 4-Hydroxybenzylamine Verwandte Suche:

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