Grubbs catalyst 2nd generation

Bezeichnung:Grubbs catalyst 2nd generation

CAS-Nr246047-72-3

Englisch Name:Grubbs catalyst 2nd generation

CBNumberCB4322469

SummenformelC46H65Cl2N2PRu

Molgewicht848.98

MOL-Datei246047-72-3.mol

Grubbs catalyst 2nd generation physikalisch-chemischer Eigenschaften

Schmelzpunkt	143.5-148.5 °C(lit.)
storage temp.	2-8°C
Löslichkeit	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated)
Aggregatzustand	Solid
Farbe	Brown to Very Dark Brown to Very Dark Red
InChIKey	FCDPQMAOJARMTG-UHFFFAOYSA-L
SMILES	P(C1CCCCC1)(C1CCCCC1)(C1CCCCC1)[Ru+6](=[C-2]1N(C2C(=CC(C)=CC=2C)C)CCN1C1C(=CC(C)=CC=1C)C)([Cl-])([Cl-])=[C-2]C1C=CC=CC=1
EPA chemische Informationen	Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)- (246047-72-3)

Sicherheit

Kennzeichnung gefährlicher	F
R-Sätze:	36/37/38-11
S-Sätze:	26-36/37/39
RIDADR	1325
WGK Germany	3
F	10-23
HazardClass	4.1
PackingGroup	Ⅱ

Gefahreninformationscode (GHS)

Grubbs catalyst 2nd generation Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
pink-brown to red-purple crystals or powder
Charakteristisch
Grubbs catalyst is a kind of coordination compound used in olefin metathesis reaction, and the ligand in it has a great influence on the catalytic performance and stability of the catalyst. Grubbs second-generation catalysts are more active than first-generation catalysts and have a wider substrate range, including sterically demanding or deactivated olefins such as 1,1-disubstituted olefins and α,β-non- Saturated carbonyl compounds.
Verwenden
Grubbs Catalyst^? M204 can be used as a catalyst for ring-closing metathesis (RCM), cross-metathesis, and ring-opening metathesis polymerization (ROMP). It is also used to synthesize trisubstituted olefins with excellent functional group tolerance and selectivity via cross-metathesis and ring closing metathesis reactions.
It can also be used as a catalyst:
- To synthesize coumarins from phenolic compounds via RCM.
- To cleave secondary (E)-allyl vic-diols to aldehydes.
Verwenden
suzuki reaction
Definition
Adlhart and Chen found that ligand rotation is the difference between the activity of the first and second-generation Grubbs catalysts. This difference is brought about by a difference in the symmetry of the ligands. The phosphine ligand has a threefold symmetry, which causes a high barrier in the middle of the reaction coordinate, which is forced by the need for rotation of the phosphine. However, the barrier is absent for the second-generation Grubbs catalyst, with twofold symmetry of the NHC ligand. The rate-limiting step for second-generation catalysts is always phosphine dissociation[2].

Grubbs catalyst 2nd generation Upstream-Materialien And Downstream Produkte

Grubbs catalyst 2nd generation Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

246047-72-3, Grubbs catalyst 2nd generation Verwandte Suche:

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