N-Fluorobenzenesulfonimide

Bezeichnung:N-Fluorobenzenesulfonimide

CAS-Nr133745-75-2

Englisch Name:N-Fluorobenzenesulfonimide

CBNumberCB4156620

SummenformelC12H10FNO4S2

Molgewicht315.34

MOL-Datei133745-75-2.mol

N-Fluorobenzenesulfonimide physikalisch-chemischer Eigenschaften

Schmelzpunkt	114-116 °C
Siedepunkt	471.4±28.0 °C(Predicted)
Dichte	1.4466 (estimate)
Flammpunkt	110℃
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	Very soluble in acetonitrile, dichloromethane or THF and less soluble in toluene.
Aggregatzustand	solid
pka	-32.45±0.70(Predicted)
Farbe	white
BRN	5348902
InChIKey	RLKHFSNWQCZBDC-UHFFFAOYSA-N
CAS Datenbank	133745-75-2(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi,O
R-Sätze:	36/37/38
S-Sätze:	26-37/39
WGK Germany	3
F	10
Hazard Note	Oxidising Agent
TSCA	No
HazardClass	IRRITANT
HS Code	29242990

Gefahreninformationscode (GHS)

N-Fluorobenzenesulfonimide Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Off-white to light brown crystalline powder
Verwenden
Versatile fluorinating reagent used in the fluorination of aryls, enolates, carbanions, organolithiums, etc.
Verwenden
N-Fluorobenzenesulfonimide fluorinates aromatics, enolates, azaenolates and carbanions in high yield. It is used for diastereoselective fluorination of Li enolates of chiral carboximides, for directed fluorination of ortho-lithiated aromatics and for a review of electrophilic N-F fluorinating agents. Asymmteric fluorinations is effected in the presence of a Pd-BINAP catalyst system at room temperature in an ionic liquid. It is a reagent employed in a palladium-catalyzed enantioselective fluorination of t-butoxycarbonyl lactones and lactams. It is also used in the electrophilic difluorination of dihalopyridines with butyl lithium and in the direct conversion of alcohols to dibenzenesulfonamides with triphenylphosphine.
Application
N-Fluorobenzenesulfonimide is a mild electrophilic fluorinating reagent, that can also be used as a strong oxidant for the promotion of reductive elimination from transition metals.
Allgemeine Beschreibung
N-Fluorobenzenesulfonimide (NFSi) is a commonly used electrophilic fluorinating agent in organic synthesis to introduce fluorine into neutral organic molecules. It is also used to fluorinate nucleophilic substrates such as reactive organometallic species and malonate anions.
NFSi can be synthesized by the reaction of benzenesulfonimide with fluorine.

N-Fluorobenzenesulfonimide Upstream-Materialien And Downstream Produkte

N-Fluorobenzenesulfonimide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

133745-75-2, N-Fluorobenzenesulfonimide Verwandte Suche:

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