N-(Carbamoylmethyl)taurin

Bezeichnung:N-(Carbamoylmethyl)taurin

CAS-Nr7365-82-4

Englisch Name:ACES

CBNumberCB3663938

SummenformelC4H10N2O4S

Molgewicht182.2

MOL-Datei7365-82-4.mol

Synonyma

N-(Carbamoylmethyl)taurin

N-(Carbamoylmethyl)taurin physikalisch-chemischer Eigenschaften

Schmelzpunkt	>220 °C (dec.)(lit.)
Siedepunkt	404.49℃
Dichte	1.484±0.06 g/cm3(Predicted)
Dampfdruck	0Pa at 25℃
storage temp.	room temp
Löslichkeit	H₂O: 0.1 M at 20 °C, clear, colorless
Aggregatzustand	Crystals
Farbe	White
PH	2.5-4.5 (25℃, 0.1M in H2O)
pka	6.8(at 25℃)
Säure-Base-Indikators(pH-Indikatoren)	6.1 - 7.5
Wasserlöslichkeit	soluble
maximale Wellenlänge (λmax)	λ: 260 nm Amax: 0.008 λ: 280 nm Amax: 0.005
Merck	14,36
BRN	2253770
InChIKey	DBXNUXBLKRLWFA-UHFFFAOYSA-N
LogP	-4.49 at 25℃
CAS Datenbank	7365-82-4(CAS DataBase Reference)
EPA chemische Informationen	Ethanesulfonic acid, 2-[(2-amino-2-oxoethyl)amino]- (7365-82-4)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	37/39-26-24/25
WGK Germany	3
TSCA	Yes
HS Code	29241900

Gefahreninformationscode (GHS)

ACES Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
ACES is a zwitterionic buffering agent used in biochemistry and molecular biology that was first selected and described by Good et al. It is a paraacetamide buffer suitable for environments with a pH of 6.1 - 7.5. ACES can be used as a buffer component in cell culture media for use in agarose and polyacrylamide electrophoresis and in isoelectric focusing of proteins. It forms complexes with most common metals, and the formation constant should be taken into account when using such buffers in solutions containing metal ions.
Chemische Eigenschaften
ACES (N-(Carbamoylmethyl)taurine) is white crystals
Verwenden
ACES is used as a Good's buffer is an ideal separator in the resolution of protein systems, a zwitterionic compound used in biochemical and biological research.
Verwenden
N-(Carbamoylmethyl)taurine can be used to study biological buffers and zwitterionic compounds. ACES has been used in a study to determine the levels of ibuprofen and flurbiprofen in pharmaceuticals by capillary zone electrophoresis.
Verwenden
Buffer for biological systems.
Definition
ChEBI: ACES (N-(2-acetamido)-2-aminoethanesulfonic acid) is a Good's buffer substance, pKa = 6.9 at 20 ℃. It is an ACES and an amino sulfonic acid. It is a tautomer of a 2-[(2-amino-2-oxoethyl)ammonio]ethanesulfonate.
synthetische
In the presence of the reaction solvent tetrahydrofuran, add nitrogen-containing reagent ammonia into the reactor to react with the raw material, wherein the molar ratio of ammonia to theraw material is 1:1. The reaction temperature is 60°C, the reaction pressure is 1 MPa (gauge pressure), and the reaction time is 8 hours. After the reaction is completed, it is acidified to generate ACES. Then spin off the solvent tetrahydrofuran, add ethyl acetate, wash twice with water, dry with anhydrous sodium sulfate, and spin off the ethyl acetate to obtain the crude ACES. Purification stepIn the reactor, the purified solvent tetrahydrofuran was added to dissolve the crude ACES, recrystallized at low temperature, the insoluble matter was removed by suction, and the filtrate was rotary evaporated to remove tetrahydrofuran to obtain refined ACES.
läuterung methode
Recrystallise ACES from hot aqueous EtOH. [Perrin & Dempsey Buffers for pH and Metal Ion Control Chapman & Hall, London 1974, Beilstein 4 III 1707.]

N-(Carbamoylmethyl)taurin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

7365-82-4, ACES Verwandte Suche:

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