Taurin

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P264：Nach Gebrauch gründlich waschen.

  P264：Nach Gebrauch gründlich waschen.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P304+P340：BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

  P405：Unter Verschluss aufbewahren.

Taurine Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

• S-Sätze Betriebsanweisung:

  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
  S24/25:Berührung mit den Augen und der Haut vermeiden.

• Beschreibung

  Taurine is a sulfur-containing amino acid with simple structure in animals. Its chemical name is 2-aminoethanesulfonic acid. Its molecular formula is C2H7NO3S and its molecular weight is 125.15. It is odorless and slightly sour. Its dilute solution is neutral and stable to heat. It combines with cholic acid in human and animal bile and exists in the form of binding; In brain, ovary, heart, liver, milk, pineal gland, pituitary, retina, adrenal gland and other tissues, it exists in free form, with a total amount of 12-18g, but does not participate in protein synthesis. Taurine is a conditionally essential amino acid for human body and plays an important role in the development of fetal and infant nervous system. Taurine can be widely used in medicine, food additives, fluorescent brighteners, organic synthesis and other fields. It can also be used as biochemical reagent, wetting agent, pH buffer and so on.

• Chemische Eigenschaften

  White crystalline powder

• Chemische Eigenschaften

  Taurine is a naturally occurring amino acid with a bitter taste and sharp flavor. It is a nonessential amino acid by definition because the body can synthesize it from methionine and cysteine.

• Occurrence

  Reported found in beef, black beans, chicken, chick peas, clams, cod, fish, lamb, milk, octopus, oysters, pistachios, pork, scallops, shrimp and other natural sources.

• Verwenden

  Taurine is an organic acid found in animal tissues and is a major constituent of bile. Taurine has many biological roles such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization and modulation of calcium signaling. It is an amino acid nutritional supplement that is used to treat taurine-deficiency diseases such as dilated cardiomyopathy, a type of heart disease.

• Definition

  ChEBI: Taurine is an amino sulfonic acid that is the 2-amino derivative of ethanesulfonic acid. It is a naturally occurring amino acid derived from methionine and cysteine metabolism. An abundant component of fish- and meat-based foods, it has been used as an oral supplement in the treatment of disorders such as cystic fibrosis and hypertension. It has a role as a human metabolite, an antioxidant, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a glycine receptor agonist, a nutrient and a radical scavenger. It is a conjugate acid of a 2-aminoethanesulfonate. It is a tautomer of a taurine zwitterion.

• Biosynthese

  In addition to the intake of taurine directly from the diet, the animal body can also biosynthesis in the liver. The intermediate product of methionine and cysteine metabolism, cysteine, is decarboxylated to taurine by cysteine decarboxylase (CSAD), and then oxidized to taurine. CSAD is considered to be the rate limiting enzyme of taurine biosynthesis in mammals, and compared with other mammals, the activity of human CSAD is lower, which may be due to the low taurine synthesis ability in human body. Taurine can participate in the formation of taurocholic acid and hydroxyethyl sulfonic acid after decomposition in vivo. The amount of taurine required depends on cholic acid binding capacity and muscle content.

• Allgemeine Beschreibung

  Taurine, which has chemistry similar to other amino acids, is important in several of the body's metabolic processes. Taurine is thought to have antioxidant properties. But little is known about the effects of long-term supplemental taurine use.

• Air & Water Reaktionen

  Water soluble.

• Reaktivität anzeigen

  Taurine is an amino acid found in combination with bile acids [Hawley].

• Hazard

  Toxic by ingestion.

• Health Hazard

  ACUTE/CHRONIC HAZARDS: Taurine evolves highly toxic fumes when heated to decomposition, and may cause irritation on contact.

• Brandgefahr

  Flash point data are not available for Taurine, but Taurine is probably combustible.

• Biologische Aktivität

  One of the most abundant free amino acids in the brain. A partial agonist at the inhibitory glycine receptor.

• Biochem/physiol Actions

  Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

• Pharmakologie

  Taurine is an organic osmotic regulator. It not only participates in the regulation of cell volume, but also provides the basis for the formation of bile salts. It also plays an important role in the modulation of intracellular free calcium concentration. Although taurine is a special amino acid not included in proteins, taurine is the most abundant amino acid in brain, retina and muscle tissue. Taurine is widely used, such as in the function of central nervous system, cell protection, cardiomyopathy, renal insufficiency, abnormal development of renal function and retinal nerve injury. Almost all eye tissues contain taurine. The quantitative analysis of rat eye tissue extract showed that taurine was the most abundant amino acid in retina, vitreous, lens, cornea, iris and ciliary body. Many studies have found that taurine is an active substance that regulates the normal physiological activities of the body. It has the functions of anti-inflammatory, analgesic, maintaining the osmotic pressure balance of the body, maintaining normal visual function, regulating the calcium balance of cells, reducing blood sugar, regulating nerve conduction, participating in endocrine activities, regulating lipid digestion and absorption, increasing the contractility of the heart, improving the immune capacity of the body, and enhancing the antioxidant capacity of cell membrane Protect a wide range of biological functions such as cardiomyocytes.

• Sicherheitsprofil

  Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.

• Veterinary Drugs and Treatments

  Taurine has proven beneficial in preventing retinal degeneration and the prevention and treatment of taurine-deficiency dilated cardiomyopathy in cats. Although modern commercial feline diets have added taurine, some cats still develop taurine-deficiency associated dilated cardiomyopathy. It may also be of benefit in taurine (±carnitine) deficient cardiomyopathy in American Cocker Spaniels and certain other breeds such as, Golden Retrievers, Labrador Retrievers, Newfoundlands, Dalmations, Portuguese Water Dogs, and English Bulldogs. Preliminary studies have shown evidence that it may be useful as adjunctive treatment for cardiac disease in animals even if taurine deficiency is not present. Because of its low toxicity, some have suggested it be tried for a multitude of conditions in humans and animals; unfortunately, little scientific evidence exists for these uses.

• Lager

  Store at RT

Taurine Upstream-Materialien And Downstream Produkte

Taurin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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