TAS-F

Bezeichnung:TAS-F

CAS-Nr59218-87-0

Englisch Name:TAS-F

CBNumberCB3400719

SummenformelC9H24F2N3SSi

Molgewicht272.45

MOL-Datei59218-87-0.mol

TAS-F physikalisch-chemischer Eigenschaften

storage temp.	2-8°C
Löslichkeit	R = Me, sol MeCN, pyridine, benzonitrile; partially sol THF. R = Et, sol THF, MeCN. Both react slowly with MeCN.
Aggregatzustand	powder
Farbe	White to off-white
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	8: reacts rapidly with moisture, water, protic solvents
BRN	3577020

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	14-34-37
S-Sätze:	26-36/37/39-45
RIDADR	UN 3261 8/PG 2
WGK Germany	3
F	3-10-21
Hazard Note	Corrosive/Moisture Sensitive
TSCA	No
HazardClass	8
PackingGroup	II
HS Code	2931900090

Gefahreninformationscode (GHS)

TAS-F Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R14:Reagiert heftig mit Wasser.
R34:Verursacht Verätzungen.
R37:Reizt die Atmungsorgane.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Physikalische Eigenschaften
R = Me, mp 98–101 °C; R = Et, mp 90–95 °C.
Verwenden
Tris(dimethylamino)sulfonium Difluorotrimethylsilicate is used in anhydrous fluoride ion source; synthesis of C–F compounds by nucleophilic displacement of sulfonates;promoter for electrophilic reactions of silyl enolates of ketones and esters; source of sulfonium cation capable of stabilizing or imparting high nucleophilic reactivity to other anions; activator of vinylsilanes in Pd-catalyzed cross-coupling reactions; also used for generation8 and reactions of α- and β-halo carbanions; hydrosilylation and cyanomethylation of ketones.
Verwenden
Tris(dimethylamino)sulfonium difluorotrimethylsilicate (TASF₂SiMe₃) can be used as a mild deprotecting reagent for the cleavage of silicon protecting groups.
It can also be used
- To synthesize deoxyfluoro sugars by reacting with trifluoromethanesulfonyl derivatives of partially protected sugars.
- As a reagent for the fluorination of hydroxyl-containing compounds.
synthetische
The methyl derivative is prepared by the reaction of dimethylaminotrimethylsilane and sulfur tetra- fluoride at ?70°C to rt in ether; the precipitated solid is filtered off.1a The ethyl derivative is best prepared by the reaction of N,N-diethylaminosulfur trifluoride (DAST) and diethylaminotrimethylsilane.
Allgemeine Beschreibung
Tris(dimethylamino)sulfonium difluorotrimethylsilicate is widely used in organic synthesis as a source of fluoride ion for the synthesis of fluorinated compounds by C-F bond formation. It is also used as a reagent in hydrosilylation, cyanomethylation of ketones and Pd-catalyzed cross-coupling reactions.

TAS-F Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

59218-87-0, TAS-F Verwandte Suche:

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