Retinyl propionate Struktur

Retinylpropionat

Bezeichnung:Retinylpropionat

CAS-Nr7069-42-3

Englisch Name:Retinyl propionate

CBNumberCB3188398

SummenformelC23H34O2

Molgewicht342.51

MOL-Datei7069-42-3.mol

Synonyma

Retinylpropionat

Retinylpropionat physikalisch-chemischer Eigenschaften

Siedepunkt	453.7±14.0 °C(Predicted)
Dichte	0.963±0.06 g/cm3(Predicted)
Dampfdruck	0-0Pa at 20-96.2℃
Flammpunkt	128 °C
storage temp.	2-8°C
Löslichkeit	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
Aggregatzustand	Oil
Farbe	Pale Yellow to Yellow
BRN	2475675
Stabilität	Light Sensitive
LogP	9.12 at 25℃

Sicherheit

Kennzeichnung gefährlicher	Xn,T
R-Sätze:	38-63-53-61
S-Sätze:	53-45
WGK Germany	1
F	1-8-10

Gefahreninformationscode (GHS)

Retinyl propionate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R38:Reizt die Haut.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
Retinyl propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare".Similar to retinyl palmitate, retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together.
Chemische Eigenschaften
Thick Yellow Oil
Verwenden
Retinyl Propionate is a Vitamin A ester derivative. Retinyl Propionate is a hypermitotic agent that is used in cosmetic formulations.This compound contains an unknown cis isomer.
Biochem/physiol Actions
Retinyl propionate, a derivative of retinol, is a fatty acid that is used as a sample preparation for copper-complexed collagen[1]. In metabolic processes, retinyl propionate is metabolized primarily into retinol (ROL) in the viable epidermis and dermis whereas ROL is esterified into retinyl palmitate (RPalm) and metabolized into the inactive retinoid 14‐hydroxy‐4,14‐retro‐retinol (14‐HRR)[2]. Retinol and its derivatives effectively intervene in the skin aging process. The matrix effect of retinyl propionate can be seen in the skin cells, bone cells, and cartilage tissue. Retinyl propionate has been shown to increase calcium pantothenate transport rates in human serum and also has a film-forming polymer effect.
Nebenwirkungen
Side effects of using retinol may include: redness, irritation, burning, itching, dry skin, flaking and peeling of the skin, increased sensitivity to the sun, and skin cancer.
Structure and conformation
Retinyl propionate is closest in molecular size to pure retinoic acid with just three additional carbons. Vitamin A palmitate has an additional 16 carbons, making it too large to reach the dermis effectively.
Einzelnachweise
[1] Wang Q, et al. The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging. Journal of Cosmetic Dermatology, 2023; 22: 2040-2049.
[2] Yang Y, et al. Hydrophobically modified inulin based nanoemulsions for enhanced stability and transdermal delivery of retinyl propionate. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022; 653: 129883.

Retinyl propionate Upstream-Materialien And Downstream Produkte

Retinylpropionat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

7069-42-3, Retinyl propionate Verwandte Suche:

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