N-carbamoylmethyliminodi(essigsure)

Bezeichnung:N-carbamoylmethyliminodi(essigsure)

CAS-Nr26239-55-4

Englisch Name:N-(2-Acetamido)iminodiacetic acid

CBNumberCB3183520

SummenformelC6H10N2O5

Molgewicht190.15

MOL-Datei26239-55-4.mol

Synonyma

N-carbamoylmethyliminodi(essigsure)

N-carbamoylmethyliminodi(essigsure) physikalisch-chemischer Eigenschaften

Schmelzpunkt	219 °C (dec.)(lit.)
Siedepunkt	325.64°C (rough estimate)
Dichte	1.4957 (rough estimate)
Dampfdruck	0Pa at 25℃
Brechungsindex	1.5010 (estimate)
storage temp.	room temp
Löslichkeit	1 M NaOH: 0.05 M at 20 °C, clear, colorless
Aggregatzustand	Powder
Farbe	White to almost white
PH	1.5-3.0 (25℃, 0.01M in H2O)
pka	6.6(at 25℃)
Säure-Base-Indikators(pH-Indikatoren)	6.0 - 7.2
Wasserlöslichkeit	soluble
maximale Wellenlänge (λmax)	λ: 260 nm Amax: 0.20 λ: 280 nm Amax: 0.05
Merck	14,147
BRN	1787181
InChIKey	QZTKDVCDBIDYMD-UHFFFAOYSA-N
LogP	-3.12 at 20℃
CAS Datenbank	26239-55-4(CAS DataBase Reference)
EPA chemische Informationen	Glycine, N-(2-amino-2-oxoethyl)-N-(carboxymethyl)- (26239-55-4)

Sicherheit

S-Sätze:	24/25
WGK Germany	3
TSCA	Yes
HazardClass	IRRITANT
HS Code	29241900

Gefahreninformationscode (GHS)

N-(2-Acetamido)iminodiacetic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
N-(2-Acetamido)iminodiacetic acid is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2.
Chemische Eigenschaften
N-(2-Acetamido)iminodiacetic acid is white to almost white powder
Verwenden
N-(2-Acetamido)iminodiacetic acid (ADA) could prevents oxidation and irreversible denaturation of proteins while conducting gel electrophoresis. Furthermore studies suggest that ADA interferes with BCA and Lowry protein assays. Also ADA often chelates metal ions such as Mn(II), Cu(II), Ni(II), Zn(II), and Co(II) in a 2:1 at or below physiological pH values. Moreover, ADA is soluble in sodium hydroxide and absorbs UV radiation in the range below 260nm.
Verwenden
N-(2-Acetamido)iminodiacetic acid is buffer for biological systems and chelator for metals.
Verwenden
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4).Used to prepare immobilized pH gradients.
Application
ADA, or N-(2-Acetamido)iminodiacetic acid, can be used to study biological buffers and zwitterionic compounds. ADA has been used in a study to describe the application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column.
Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4). Used to prepare immobilized pH gradients.
Definition
ChEBI: 2,2'-[(2-amino-2-oxoethyl)imino]diacetic acid is a tricarboxylic acid amide that is a Good's buffer substance, pKa = 6.6 at 20 ℃. It is a dicarboxylic acid, a tricarboxylic acid amide and an ADA. It is functionally related to a nitrilotriacetic acid. It is a conjugate acid of a 2,2'-[(2-amino-2-oxoethyl)imino]diacetate(1-).
Flammability and Explosibility
Not classified
läuterung methode
Dissolve ADA in water, add one equivalent of NaOH solution (to final pH of 8-9), then acidify with HCl to precipitate the free acid. This is filtered off, washed with water and dried in vacuo. [Beilstein 4 IV 2441.]

N-(2-Acetamido)iminodiacetic acid Upstream-Materialien And Downstream Produkte

N-carbamoylmethyliminodi(essigsure) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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