Epoprostenol

Epoprostenol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Prostacyclin,ZYF Pharm Chemical

• Verwenden

  Inhibitor (platelet). [Names previously used: Prostacyclin, PGI2, Prostagland in I2, Prostaglandin X, PGX].

• Definition

  ChEBI: Prostaglandin I2 is a prostaglandins I. It has a role as a mouse metabolite. It is a conjugate acid of a prostaglandin I2(1-).

• Manufacturing Process

  Preparation of prostacyclin:
  Pig aortas were stripped of adventitia, snap frozen in liquid nitrogen, crushed into a fine powder, resuspended in 0.05 M Tris buffer (pH 7.5) (1:4, w:v) andhomogenised at high speed in a Polytron (KIMENATIC, LUCERNE, SWITZERLAND) homogenizer. The homogenate was centrifuged for 15 min and the resulting supernatant centrifuged again for 5 min. The pellet was discarded, while the pellet obtained after centrifugation of the supernatant was resuspended in deionized water and lyophilized. An average yield of 150 mg of aortic microsomal powder (51% protein) per 100 g of aortic tissue was obtained.

• Trademarks

  Flolan (GlaxoSmithKline).

• Therapeutic Function

  Platelet aggregation inhibitor, Antimetastatic

Epoprostenol Upstream-Materialien And Downstream Produkte

Epoprostenol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(40)Suppliers

35121-78-9, Epoprostenol Verwandte Suche: