Malonamid

Bezeichnung:Malonamid

CAS-Nr108-13-4

Englisch Name:Malonamide

CBNumberCB2418973

SummenformelC3H6N2O2

Molgewicht102.09

MOL-Datei108-13-4.mol

Synonyma

Malonamid

Malonamid physikalisch-chemischer Eigenschaften

Schmelzpunkt	172-175 °C (lit.)
Siedepunkt	191.38°C (rough estimate)
Dichte	1.3516 (rough estimate)
Brechungsindex	1.5110 (estimate)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Soluble in HCl.
Aggregatzustand	powder to crystal
pka	7.00±0.70(Predicted)
Farbe	White to Almost white
Wasserlöslichkeit	180 g/L (20 ºC)
BRN	1751401
InChI	InChI=1S/C3H6N2O2/c4-2(6)1-3(5)7/h1H2,(H2,4,6)(H2,5,7)
InChIKey	WRIRWRKPLXCTFD-UHFFFAOYSA-N
SMILES	C(N)(=O)CC(N)=O
CAS Datenbank	108-13-4(CAS DataBase Reference)
NIST chemische Informationen	Propanediamide(108-13-4)
EPA chemische Informationen	Propanediamide (108-13-4)

Sicherheit

S-Sätze:	22-24/25
WGK Germany	2
RTECS-Nr.	ON9125000
TSCA	Yes
HS Code	29241900

Gefahreninformationscode (GHS)

Malonamide Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.
Chemische Eigenschaften
White crystalline powder
Verwenden
The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare-earth ions from nitric acid medium.
Verwenden
Malonamide is a reagent for fluorimetric determination of reducing carbohydrates. The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare earth elements from nitric acid medium.
Verwenden
Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.
Definition
ChEBI: Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.
Allgemeine Beschreibung
The malonamide derivatives are obtained by the one-pot, five-component condensation reaction of isocyanide, Meldrum′s acid, arylidene malononitrile, and two amine molecules in CH₂Cl₂.
Hazard
Mildly toxic by ingestion.
Synthese
The synthesis of Malonamide is as follows:
A typical reaction was carried out in a 10 mL flask. Benzonitrile (2 mmol), CuII-4 ? (0.2 g), acetaldoxime (6 mmol) and MeOH (4 mL) were stirred at 65 °C for 4 h. The solid was filtered, washed with MeOH and the filtrate evaporated. The residue was subjected to GC-MS analysis and NMR spectroscopy. The filtered catalyst can be recycled after drying at about 150 °C for 1 h.
läuterung methode
Crystallise the amide from water. [Beilstein 2 IV 1887.]

Malonamide Upstream-Materialien And Downstream Produkte

Malonamid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

108-13-4, Malonamide Verwandte Suche:

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