Hydroxyecdysone

Bezeichnung:Hydroxyecdysone

CAS-Nr5289-74-7

Englisch Name:Hydroxyecdysone

CBNumberCB1692996

SummenformelC27H44O7

Molgewicht480.64

MOL-Datei5289-74-7.mol

Hydroxyecdysone physikalisch-chemischer Eigenschaften

Schmelzpunkt	242-244 °C
Siedepunkt	498.63°C (rough estimate)
Dichte	1.0760 (rough estimate)
Brechungsindex	1.5800 (estimate)
storage temp.	Sealed in dry,Store in freezer, under -20°C
Löslichkeit	alcohol: soluble
Aggregatzustand	powder
pka	14.13±0.70(Predicted)
Farbe	white
Merck	13,3525
BRN	1917578
InChIKey	NKDFYOWSKOHCCO-YPVLXUMRSA-N
SMILES	O[C@@]12CC[C@]([H])([C@](O)(C)[C@H](O)CCC(O)(C)C)[C@]1(CC[C@]1([H])[C@]3(C[C@H](O)[C@H](O)C[C@@]3([H])C(=O)C=C21)C)C \|&1:1,4,6,9,17,20,22,24,26,29,r\|
LogP	-0.270 (est)
CAS Datenbank	5289-74-7(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	22-24/25-36-26
WGK Germany	2
RTECS-Nr.	FZ8060000
F	10
HS Code	29372900

Gefahreninformationscode (GHS)

Hydroxyecdysone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White or off-white powder, odorless, hygroscopic, the color gradually becomes darker when exposed to light. Soluble in ethanol, slightly soluble in acetone, slightly soluble in hot water, ethyl acetate, chloroform, almost insoluble in ether, derived from Leulu, Achyranthes bidentata, Cyanotis, arachnoidea, Pfaffia glomerata.
Verwenden
20-Hydroxyecdysone has been used:
in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
as an insect molting hormone
Definition
ChEBI: 20-hydroxyecdysone is an ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. It has a role as a plant metabolite and an animal metabolite. It is a 20-hydroxy steroid, an ecdysteroid, a 14alpha-hydroxy steroid, a 3beta-sterol, a 2beta-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid and a phytoecdysteroid. It is functionally related to an ecdysone.
Biochem/physiol Actions
20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).
Lager
+4°C
läuterung methode
Crystallise -ecdyson from water, tetrahydrofuran/pet ether, MeOH and EtOAc after chromatographic purification. It has max (EtOH) at 240nm ( 12,670 M-1cm-1). [Also IR & NMR: Hüppi & Siddall J Am Chem Soc 89 6799 1967, Kametani et al. Tetrahedron Lett 21 4855 1980, Beilstein 8 IV 343.]

Hydroxyecdysone Upstream-Materialien And Downstream Produkte

Hydroxyecdysone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

5289-74-7, Hydroxyecdysone Verwandte Suche:

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