Dihydralazin

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H314：Verursacht schwere Verätzungen der Haut und schwere Augenschäden.

• Sicherheit

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

  P310：Sofort GIFTINFORMATIONSZENTRUM/Arzt/ anrufen.

Ophthazin Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Nepresol,Novartis

• Verwenden

  Ophthazin is an antihypertensive agent of the hydrazine class used during pregnancies in dialysis patients with familial mediterranean fever and cystinosis under hemodialysis.

• Definition

  ChEBI: Dihydralazine is a member of phthalazines.

• Manufacturing Process

  115 parts of hydrazine hydrate in 80 parts 50% acetic acid were added to 128 parts of phthalic acid dinitrile in 250 parts dioxane. The mixture was heated at the temperature 95°C for 3 hours with stirring. After 20 minutes the crystallization and discharging of NH3 began. The orange needles were filtered off after cooling. The product was washed with dioxane and ethanol and recrystallized from 3000 parts of water to yield 110 parts colorless needles of 1,4-dihydrazino-phthalazine; MP: 191°-193°C (decomp.). The crystals were getting a little orange color by standing because of a reaction with an air oxygen.

• Therapeutic Function

  Antihypertensive

• Sicherheitsprofil

  Poison by intravenous route. Anexperimental teratogen. When heated to decomposition itemits toxic fumes of NOx.

Ophthazin Upstream-Materialien And Downstream Produkte

Dihydralazin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(51)Suppliers

484-23-1, Ophthazin Verwandte Suche: