Propranolol

Propanolol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Propranolol was responsible for sensitisation of workers in drug synthesis. In one case, epichlorhydrin was used for the production of both propranolol and oxprenolol.

• Chemische Eigenschaften

  Colorless crystals.Soluble in water and alcohol; insoluble in benzene and ether.

• Verwenden

  Cardiac depressant (anti-arrhythmic); anti-adrenergic (β-receptor).

• Verwenden

  β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).

• Definition

  ChEBI: A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

• Indications

  Major indications of propranolol, and of many other β-blockers, include coronary heart disease, hypertension, and cardiac arrhythmias. These β-blocking agents are mainly used in arrhythmias accompanied by increased catecholamine levels, e.g., excitement, stress, or hyperthyroidism .

• Trademarks

  Inderal (Wyeth); Innopran (Reliant).

• Hazard

  Highly toxic.

• Kontakt-Allergie

  Propranolol is a beta-blocking agent that was responsible for the sensitization of workers in drug synthesis. In one case, epichlorhydrin was used for the production of drugs propranolol and oxprenolol. Crossreactivity is expected between beta-blockers.

Propanolol Upstream-Materialien And Downstream Produkte

Propranolol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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