Choline bicarbonate Struktur

Cholinhydrogencarbonat

Bezeichnung:Cholinhydrogencarbonat

CAS-Nr78-73-9

Englisch Name:Choline bicarbonate

CBNumberCB0301110

SummenformelC6H15NO4

Molgewicht165.19

MOL-Datei78-73-9.mol

Synonyma

Cholinhydrogencarbonat

Cholinhydrogencarbonat physikalisch-chemischer Eigenschaften

Dichte	1.17 g/mL at 25 °C (lit.)
Dampfdruck	23.904hPa at 25℃
Brechungsindex	n20/D 1.45
storage temp.	2-8°C
Löslichkeit	Methanol (Sparingly), Water (Soluble)
Aggregatzustand	Colourless Solution
Wasserlöslichkeit	750g/L at 20℃
InChIKey	DQKGOGJIOHUEGK-UHFFFAOYSA-M
CAS Datenbank	78-73-9(CAS DataBase Reference)
EPA chemische Informationen	Choline carbonate (1:1) (78-73-9)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-37/39
WGK Germany	3

Gefahreninformationscode (GHS)

Choline bicarbonate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Colorless liquid.Miscible with water.
Verwenden
Choline, a water soluble essential nutrient, is used by the body to make phosphatidylcholine phosphatides and neurotransmitter such as acetylcholine. Choline is used to study a wide range of biological processes from stem cell development to neurological disease studies. Also, An alkaline intermediate useful for preparing salts.
Verwenden
Choline Bicarbonate is compound is used for protein delivery, Alkaline catalyst, intermediate for choline salts and surfactants.
Reaktionen
[1CA:3PE] - (1:2) Choline 3-Pentenoate Synthesis

An oil bath was heated to approximately 60°C and the stirrer on the hot plate was adjusted to 410 RPM. 3.5022g of 3-Pentenoic acid (MW: 100.12g/mol) were weighed and placed in a 500 mL RBF. 3.6254g of Choline Bicarbonate (MW: 165.19g/mol) were weighed and added to the RBF in a drop-wise manner using a glass Pasteur pipette. Less than 1 mL of milli-Q water was used to rinse the master pipette and weighing materials, the milli-Q was then added to the RBF. The mixture was left stirring on heat overnight for approximately 24 hours. The mixture was then placed on the rotary-evaporator and set to 15 mbar for just over 1 hour in order to evaporate any remaining solvents. The mass of the final product was weighed and noted; 4.5891g of [1CA:3PE] were obtained. The solution was then placed in the vacuum oven set at 60°C for over 48 hours with the top left off. Time sensitivity during this step was not as imperative as other steps since the purpose of this step was to dry out any remaining solvents or water in the IL. Once removed from the vacuum oven, the solution was reweighed and an NMR was obtained for characterization purposes. The final mass of [1CA:3PE] being 4.4934g, resulting in a total percent yield of 86.74%. 1H NMR (400 MHz, DMSO) δ 9.47 (s, 1H), 5.52 (dtd, J = 14.0, 7.0, 1.8 Hz, 2H), 5.37 (dq, J = 13.3, 6.3 Hz, 2H), 3.84 (dq, J = 5.8, 2.7 Hz, 2H), 3.44 (dd, J = 6.1, 3.9 Hz, 2H), 3.14 (s, 9H), 2.80 (d, J = 7.0 Hz, 4H), 1.61 (dd, J = 6.4, 1.8 Hz, 6H).
[1] GALLOWAY J D. The Synthesis and Characterization of Ionic Liquids using Nitrogen-Based Cations for Transdermal Delivery[C]. 2022.
Hazard
Choline bicarbonate can cause skin and eye irritation, as well as potential respiratory irritation.
Biochem/physiol Actions
Acyl group acceptor

Choline bicarbonate Upstream-Materialien And Downstream Produkte

Cholinhydrogencarbonat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

78-73-9, Choline bicarbonate Verwandte Suche:

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