trans-(±)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-olhydrochlorid

Bezeichnung:trans-(±)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-olhydrochlorid

CAS-Nr36282-47-0

Englisch Name:TRAMADOL HYDROCHLORIDE

CBNumberCB0251095

SummenformelC16H26ClNO2

Molgewicht299.84

MOL-Datei36282-47-0.mol

Synonyma

trans-(±)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-olhydrochlorid

trans-(±)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-olhydrochlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	178-181 °C
storage temp.	2-8°C
Löslichkeit	Freely soluble in water and in methanol, very slightly soluble in acetone.
Aggregatzustand	solid
Farbe	white to off-white

Sicherheit

Kennzeichnung gefährlicher	Xn,N
R-Sätze:	22-51/53
S-Sätze:	61
RIDADR	UN 2811 6.1/PG 3
WGK Germany	2
HS Code	2922504500
Toxizität	mouse,LD50,intravenous,61700ug/kg (61.7mg/kg),Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 114, 1978.

Gefahreninformationscode (GHS)

TRAMADOL HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
Beschreibung
cis-Tramadol (Item No. 15919) is an analytical reference material categorized as an opioid. cis-Tramadol is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.
Beschreibung
cis-Tramadol (hydrochloride) (CRM) (Item No. ISO60149) is a certified reference material categorized as an opioid. cis-Tramadol is regulated as a Schedule IV compound in the United States. cis-Tramadol (hydrochloride) (CRM) (Item No. ISO60149) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
Chemische Eigenschaften
White Solid
Verwenden
An analgesic.
Verwenden
cis-Tramadol is an analgesic that activates the μ-opioid receptor (IC50 = 7.6 μM). It also inhibits serotonin and norepinephrine reuptake and blocks voltage-gated sodium channels. This product is intended for forensic and research applications.[Cayman Chemical]
Definition
ChEBI: (R,R)-tramadol hydrochloride is a hydrochloride resulting from the reaction of (R,R)-tramadol with 1 molar equivalent of hydrogen chloride; the (R,R)-enantiomer of the racemic opioid analgesic tramadol hydrochloride, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a nicotinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist and a serotonin uptake inhibitor. It contains a (R,R)-tramadol(1+). It is an enantiomer of a (S,S)-tramadol hydrochloride.

36282-47-0, TRAMADOL HYDROCHLORIDE Verwandte Suche:

Send Inquriy