Cyclohexanol

Bezeichnung:Cyclohexanol

CAS-Nr108-93-0

Englisch Name:Cyclohexanol

CBNumberCB7852772

SummenformelC6H12O

Molgewicht100.16

MOL-Datei108-93-0.mol

Synonyma

Cyclohexanol

Cyclohexylalkohol

Hexahydrophenol

Cyclohexanol physikalisch-chemischer Eigenschaften

Schmelzpunkt	20-22 °C (lit.)
Siedepunkt	160-161 °C (lit.)
Dichte	0.948 g/mL at 25 °C (lit.)
Dampfdichte	3.5 (vs air)
Dampfdruck	0.98 mm Hg ( 25 °C)
Brechungsindex	n20/D 1.465(lit.)
Flammpunkt	67 °C
storage temp.	Store below +30°C.
Löslichkeit	40g/l
Aggregatzustand	Liquid After Melting
pka	16
Farbe	Clear colorless
Geruch (Odor)	Like camphor.
Relative polarity	0.509
PH	6.5 (40g/l, H2O, 20℃)
Explosionsgrenze	2-11.2%(V)
Geruchsart	camphoreous
Wasserlöslichkeit	3.6 g/100 mL (20 ºC)
Sensitive	Hygroscopic
Merck	14,2725
BRN	906744
Henry's Law Constant	16.9 at 50.00 °C, 34.4 at 60.00 °C (headspace-GC, Hovorka et al., 2002)
Expositionsgrenzwerte	TLV-TWA 200 mg/m³ (50 ppm) (ACGIH); IDLH 3500 ppm (NIOSH).
Dielectric constant	15.0（25℃）
Stabilität	Stable. Incompatible with oxidizing agents. Reacts violently with oxidizing agents such as hydrogen peroxide and nitric acid, even at room temperature, to form an explosive material. Hygroscopic. Combustible.
LogP	1.25 at 25℃
CAS Datenbank	108-93-0(CAS DataBase Reference)
NIST chemische Informationen	Cyclohexanol(108-93-0)
EPA chemische Informationen	Cyclohexanol (108-93-0)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	20/22-37/38
S-Sätze:	24/25
OEB	A
OEL	TWA: 50 ppm (200 mg/m3) [skin]
WGK Germany	1
RTECS-Nr.	GV7875000
F	21
Selbstentzündungstemperatur	572 °F
TSCA	Yes
HS Code	2906 12 00
Giftige Stoffe Daten	108-93-0(Hazardous Substances Data)
Toxizität	LD50 orally in rats: 2.06 g/kg (Smyth)
IDLA	400 ppm

Gefahreninformationscode (GHS)

Cyclohexanol Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE, HYGROSKOPISCHE FLüSSIGKEIT ODER WEISSE KRISTALLE MIT CHARAKTERISTISCHEM GERUCH.
CHEMISCHE GEFAHREN
Reagiert sehr heftig mit starken Oxidationsmitteln. Greift Kunststoff an.
ARBEITSPLATZGRENZWERTE
TLV: 50 ppm (als TWA); Hautresorption; (ACGIH 2005).
MAK: 50 ppm 210 mg/m? Spitzenbegrenzung: überschreitungsfaktor I(1); Hautresorption; Schwangerschaft: Gruppe D (DFG 2006).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation und durch Verschlucken.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C tritt eine gesundheitsschädliche Kontamination der Luft nicht oder nur sehr langsam ein
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen, die Haut und die Atemwege. Möglich sind Auswirkungen auf das Zentralnervensystem.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Die Flüssigkeit entfettet die Haut.
LECKAGE
Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Verschüttetes Material in abdichtbaren Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste mit viel Wasser wegspülen. Persönliche Schutzausrüstung: Atemschutzfilter für organische Gase und Dämpfe.
R-Sätze Betriebsanweisung:
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
R37/38:Reizt die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Aussehen Eigenschaften
C6H12O; Cyclohexylalkohol, Hexahydrophenol. Farblose Flüssigkeit mit charakteristischem, kampferartigem Geruch.
Gefahren für Mensch und Umwelt
Gesundheitsschädlich beim Einatmen und verschlucken. Reizt die Atmungsorgane und die Haut. Nach Aufnahme, auch über die Haut, kommt es zu ZNS-Störungen.
Nicht mit Alkalimetallen und starken Oxidationsmitteln in Berührung bringen.
LD₅₀(oral, Ratte): 2060 mg/kg
Schutzmaßnahmen und Verhaltensregeln
Schutzhandschuhe als kurzzeitiger Spritzschutz.
Verhalten im Gefahrfall
Dämpfe nicht einatmen.
Mit flüssigkeitsbindendem Material, z.B. Rench Rapid aufnehmen. Der Entsorgung zuführen. Nachreinigen.
Kohlendioxid, Pulver, Schaum.
Brennbar. Dämpfe schwerer als Luft.
Erste Hilfe
Nach Hautkontakt: Mit reichlich Wasser abwaschen.
Nach Augenkontakt: Mit reichlich Wasser bei geöffnetem Lidspalt mindestens 15 Minuten ausspülen. Sofort Augenarzt hinzuziehen.
Nach Einatmen: Frischluft. Arzt hinzuziehen.
Nach Verschlucken: Reichlich Wasser trinken. Erbrechen auslösen. Sofort Arzt hinzuziehen.
Nach Kleidungskontakt: Kontaminierte Kleidung sofort entfernen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
Als halogenfreie, organische Lösemittelabfälle.
Chemische Eigenschaften
Cyclohexanol is a clear, colorless to pale yellow, viscous, hygroscopic liquid with a camphor-like odor. A detection odor threshold concentration of 64 μg/m3 (155 ppbv) was reported by Punter (1983). It has a fairly high flash point and boiling range. A solvent for cellulose ethers, ester gum,shellac, low viscosity silicones and polyvinyl chloride. lt has a fairly limited use in screen inks. lt is miscible with oils and hydrocarbon solvents.
Verwenden
Cyclohexanol is used for the productionof adipic acid and caprolactam for makingnylon. Its phthalate derivatives are used forplasticizers. It is used as a stabilizer for soapsand detergents; as a solvent for lacquers,varnishes, and shellacs; and as a dye solventfor textiles.
Vorbereitung Methode
Cyclohexanol is prepared by the catalytic air oxidation of cyclohexane or by the catalytic hydrogenation of phenol. The most important use of cyclohexanol is in producing adipic acid used in the manufacture of caprolactam. Cyclohexanol is used in the manufacture of esters for use as plasticizers; it is also used as a chemical intermediate, a stabilizer, a homogenizer for various soap and detergent emulsions, and as a solvent for lacquers and varnishes . The primary routes of occupational exposure are dermal and inhalation.
Definition
ChEBI: Cyclohexanol is an alcohol that consists of cyclohexane bearing a single hydroxy substituent. The parent of the class of cyclohexanols. It has a role as a solvent. It is a secondary alcohol and a member of cyclohexanols.
Synthesis Reference(s)
Journal of the American Chemical Society, 97, p. 7118, 1975 DOI: 10.1021/ja00857a025
Tetrahedron Letters, 21, p. 2305, 1980 DOI: 10.1016/S0040-4039(00)92591-7
Allgemeine Beschreibung
Cyclohexanol appears as a colorless liquid with a camphor-like odor. Soluble in most organic liquids. Flash point 154 °F. May be toxic by inhalation or skin exposure. Vapors are narcotic in high concentrations. Irritates skin, eyes and mucus membranes. Used in making soap, lacquers, and plastics.
Air & Water Reaktionen
Less dense than water and slightly soluble in water.
Reaktivität anzeigen
Cyclohexanol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Violent reaction with nitric acid. Incompatible with strong oxidizers (chromium trioxide, nitric acid, etc.).
Health Hazard
Cyclohexanol is moderately toxic. Targetorgans are the eyes, skin, and respiratorysystem. At high concentrations cyclohexanolabsorbed through the skin may possiblyinjure the brain, kidney, and heart.
LD50 value, single oral dose (rats): 2060mg/kg
LD50 value, single intravenous dose (mice):270 mg/kg
Inhalation of vapors may cause irritationof the eyes, nose, and throat. However,because of its low vapor pressure (1.12 torrat 25°C), the health hazard due to inhalationis low. Ingestion can cause nausea,trembling, and gastrointestinal disturbances.Repeated skin contact may produce erythemaand edema.
Flammability and Explosibility
Not classified
mögliche Exposition
Cyclohexanol is used in making plac- ticizers, dry cleaning, dyebath; and textile finishing formu- lations; as a solvent for ethyl cellulose and other resins; it is used in soap manufacture; it is used as a raw material for adipic acid manufacture; as a nylon intermediate.
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
Solubility in organics
4% soluble in water, miscible with alcohol and oils. Cyclohexanol will dissolve 11% water at room temperature.
Lager
Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with cyclohexanol you should be trainedon its proper handling and storage. Before entering confinedspace where this chemical may be present, check to makesure that an explosive concentration does not exist.Cyclohexanol must be stored to avoid contact with strongoxidizers (such as chlorine, bromine, and fluorine), sinceviolent reactions occur. Metal containers involving thetransfer of this chemical should be grounded and bonded.Where possible, automatically pump liquid from drums orother storage containers to process containers. Drums mustbe equipped with self-closing valves, pressure vacuum bungs,and flame arresters. Use only nonsparking tools and equipment, especially when opening and closing containers of thischemical. Sources of ignition, such as smoking and openflames, are prohibited where this chemical is used, handled,or stored in a manner that could create a potential fire orexplosion hazard. Wherever this chemical is used, handled,manufactured, or stored, use explosion-proof electrical equipment and fittings.
Versand/Shipping
UN1986 Alcohols, toxic, flammable, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid, 6.1-Poison Inhalation Hazard, Technical Name Required.
läuterung methode
Reflux it with freshly ignited CaO, or dry it with Na2CO3, then fractionally distil it. Redistil it from Na. It is further purified by fractional crystallisation from the melt in dry air. Peroxides and aldehydes can be removed by prior washing with ferrous sulfate and water, followed by distillation under nitrogen from 2,4-dinitrophenylhydrazine, using a short fractionating column: water distils as the azeotrope. Dry cyclohexanol is very hygroscopic. The 3,4-dinitrobenzoate has m 111-112o (EtOH or aqueous EtOH) It has TOXIC vapours. [Beilstein 6 III 10, 6 IV 20.]
Inkompatibilitäten
Forms explosive mixture in air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoa- cids, epoxides. Attacks some plastics.
Waste disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinera- tor equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

Cyclohexanol Upstream-Materialien And Downstream Produkte

Cyclohexanol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

108-93-0, Cyclohexanol Verwandte Suche:

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