ML324

ML324化学性质

熔点 :>187oC (dec.)
沸点 :590.1±50.0 °C(Predicted)
密度 :1.188±0.06 g/cm3(Predicted)
储存条件 :Sealed in dry,2-8°C
溶解度 :DMSO: soluble10mg/mL, clear
酸度系数(pKa) :4.71±0.40(Predicted)
形态 :powder
颜色 :white to light brown
稳定性 :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

安全信息

ML324性质、用途与生产工艺

生物活性 ML324是一种选择性的jumonji histone demethylase (JMJD2)抑制剂，其对JMJD2E的IC50为920 nM。
体外研究 ML324 exhibits good Caco-2 cell permeability, and possesses excellent microsomal stability in the presence of both mouse and rat liver microsomes. ML324 demonstrates potent anti-viral activity against both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection by inhibiting viral IE gene expression.
体内研究 In a mouse ganglia explant model of latently infected mice, ML324 suppresses the formation of HSV plaques, and blocks HSV-1 reactivation.

ML324上下游产品信息

上游原料

下游产品

ML324 试剂级价格

ML324生产厂家

1222800-79-4, ML324相关搜索: