松茋
- CAS号:42438-89-1
- 英文名:Pinostilbene
- 中文名:松茋
- CBNumber:CB72499191
- 分子式:C15H14O3
- 分子量:242.27
- MOL File:42438-89-1.mol
- 熔点 :117-118℃
- 密度 :1.252
- 储存条件 :Keep in dark place,Inert atmosphere,2-8°C
- 溶解度 :DMSO: ≥13mg/mL
- 形态 :powder
- 颜色 :white to tan
- 危险品标志 :Xi,N
- 危险类别码 :37/38-41-50
- 安全说明 :26-39-61
- 危险品运输编号 :UN 3077 9 / PGIII
- WGK Germany :3
- 海关编码 :2909.50.5000
松茋性质、用途与生产工艺
- 用途 松茋可用于含量测定，不作其他用途。
- 生物活性 Pinostilbene 是 Pterostilbene 的一种主要代谢物。Pinostilbene 对结肠癌细胞有抑制作用。
-
体外研究
Pinostilbene (0- 40 μM; 24 hours, 48 hours) does not cause significant inhibition on the growth of normal colon cells.
Pinostilbene (20 μM, 40 μM; 24 hours, 48 hours) causes a significant and dose-dependent increase in the percentage of cells in S phase in both HCT116 and HT29 cells compared to the control cells.
Pinostilbene at μM also induces a modest increase of cell population in G2/M phase in HT29 cells.
Pinostilbene(20 μM, 40 μM; 24 hours, 48 hours) modulates expression of key signaling proteins related to cell proliferation and apoptosis.
Pinostilbene also acts as a resveratrol methylated derivative and displays protective effects against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.
Cell Viability Assay
Cell Line: HCT116 cells, HT29 cells Concentration: 24 hours, 48 hours Incubation Time: 0-100 μM Result: Inhibited the growth of two human colon cancer cells. Apoptosis Analysis
Cell Line: HCT116 cells, HT29 cells Concentration: 20 μM, 40 μM Incubation Time: 24 hours, 48 hours Result: Caused a significant and dose-dependent increase in the percentage of cells in S phase. Cell Viability Assay
Cell Line: HCT116 cells Concentration: 20 μM,40 μM Incubation Time: 24 hours, 48 hours Result: Significantly increased the expression levels of p53, Bax, cleaved caspase-3, cleaved PARP and p21 Cip1/Waf1 , while decreased the expression levels of cyclin E and p-Rb.
- 更新日期：2024/11/08
- 产品编号：HY-N3059
- 产品名称：松茋 Pinostilbene
- CAS编号：42438-89-1
- 包装：5mg
- 价格：480元
- 更新日期：2024/11/08
- 产品编号：HY-N3059
- 产品名称：松茋 Pinostilbene
- CAS编号：42438-89-1
- 包装：10mg
- 价格：780元
- 公司名称：TOKYO CHEMICAL INDUSTRY CO., LTD.
- 联系电话：03-36680489
- 电子邮件：Sales-JP@TCIchemicals.com
- 国家：日本
- 产品数：28387
- 优势度：80
