ChemicalBook CAS数据库列表 酒石酸噻吩嘧啶
酒石酸噻吩嘧啶
- CAS号:33401-94-4
- 英文名:PYRANTEL TARTRATE SALT
- 中文名:酒石酸噻吩嘧啶
- CBNumber:CB3404010
- 分子式:C15H20N2O6S
- 分子量:356.39
- MOL File:33401-94-4.mol
酒石酸噻吩嘧啶化学性质
- 熔点 :148-150°
- 储存条件 :Inert atmosphere,Room Temperature
- 溶解度 :H2O: soluble4.0ML, clear, colorless to faint yellow or tan (Solvent: 200 mg plus 4.0 mL )
- 形态 :Solid
- 颜色 :Light yellow to yellow
安全信息
酒石酸噻吩嘧啶性质、用途与生产工艺
- 生物活性 Pyrantel tartrate，一种四氢嘧啶光谱驱虫药，是烟碱乙酰胆碱受体 (nAChR) 激动剂。Pyrantel tartrate 可引起寄生虫的痉挛性肌肉麻痹。Pyrantel tartrate 可用于胃肠道线虫感染的研究。
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体外研究
Pyrantel induces Ascaris suum muscle contraction, with a pEC 50 of 7.24.
Pyrantel produces spastic paralysis of the nematode by selectively gating acetylcholine receptor ion-channels on nerve and muscle.
Pyrantel (72 h) inhibits the survival of Ancylostoma ceylanicum , Necator americanus and Trichuris muris on the third-stage larvae (IC 50 s=90.9, 2.0, and 95.5 µg/mL, respectively) and adult worms (IC 50 s=>100, 7.6, and 34.1 µg/mL, respectively). -
体内研究
Pyrantel (10 mg/kg; a single p.o.) reduces the worms in A. ceylanicum -infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.
酒石酸噻吩嘧啶上下游产品信息
上游原料
下游产品
酒石酸噻吩嘧啶生产厂家
- 公司名称：CHEMICAL LAND21
- 联系电话：--
- 电子邮件：sales21@chemicalland21.com
- 国家：韩国
- 产品数：6303
- 优势度：74
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