ChemicalBook CAS数据库列表 8-(1H-IMIDAZOL-4-YLMETHYLENE)-6,8-DIHYDRO-THIAZOLO[5,4-E]INDOL-7-ONE

8-(1H-IMIDAZOL-4-YLMETHYLENE)-6,8-DIHYDRO-THIAZOLO[5,4-E]INDOL-7-ONE

8-(1H-IMIDAZOL-4-YLMETHYLENE)-6,8-DIHYDRO-THIAZOLO[5,4-E]INDOL-7-ONE化学性质

沸点 :674.6±55.0 °C(Predicted)
密度 :1.604±0.06 g/cm3(Predicted)
储存条件 :-20°C
溶解度 :DMSO: soluble12mg/mL
酸度系数(pKa) :10.20±0.20(Predicted)
形态 :Orange to orange brown solid
颜色 :yellow to orange-brown
稳定性 :Stable for 2 years from date of purchsae as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

安全信息

8-(1H-IMIDAZOL-4-YLMETHYLENE)-6,8-DIHYDRO-THIAZOLO[5,4-E]INDOL-7-ONE性质、用途与生产工艺

生物活性 PKR-IN-C16 (C16, Imidazolo-oxindole PKR inhibitor C16) 是一种RNA-dependent protein kinase (PKR, Protein Kinase R, EIF2AK2)的特异性抑制剂。PKR-IN-C16 可在具有神经炎症成分的急性兴奋性毒性大鼠模型中阻止凋亡和 IL-1β 的产生。
靶点
Target Value
PKR
()
IL-1β
()

8-(1H-IMIDAZOL-4-YLMETHYLENE)-6,8-DIHYDRO-THIAZOLO[5,4-E]INDOL-7-ONE上下游产品信息

上游原料

下游产品

更新日期：2024/04/30
产品编号：S9668
产品名称：8-(1H-IMIDAZOL-4-YLMETHYLENE)-6,8-DIHYDRO-THIAZOLO[5,4-E]INDOL-7-ONE PKR-IN-C16
CAS编号：608512-97-6
包装：5mg
价格：1392.3元

更新日期：2024/04/30
产品编号：S9668
产品名称：8-(1H-IMIDAZOL-4-YLMETHYLENE)-6,8-DIHYDRO-THIAZOLO[5,4-E]INDOL-7-ONE PKR-IN-C16
CAS编号：608512-97-6
包装：25mg
价格：4168.71元

8-(1H-IMIDAZOL-4-YLMETHYLENE)-6,8-DIHYDRO-THIAZOLO[5,4-E]INDOL-7-ONE生产厂家

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