醋酸去氢表雄酮
- CAS号:853-23-6
- 英文名:Dehydroepiandrosterone acetate
- 中文名:醋酸去氢表雄酮
- CBNumber:CB0247928
- 分子式:C21H30O3
- 分子量:330.47
- MOL File:853-23-6.mol
- 熔点 :168-170 °C(lit.)
- 沸点 :407.89°C (rough estimate)
- 密度 :1.0998 (rough estimate)
- 蒸气压 :0Pa at 20℃
- 折射率 :1.5192 (estimate)
- 储存条件 :Refrigerator
- 溶解度 :Chloroform, DMSO (Slightly), Methanol (Slightly)
- 形态 :Solid
- 颜色 :White to Off-White
- 旋光性 (optical activity) :[α]20/D +2.4°, c = 2 in ethanol
- 水溶解性 :11.5mg/L(temperature not stated)
- InChI :InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3
- InChIKey :NCMZQTLCXHGLOK-KJBVPOJVSA-N
- SMILES :C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r|
- LogP :5.1 at 20℃
- CAS 数据库 :853-23-6
- 安全说明 :22-24/25
- WGK Germany :3
- RTECS号 :BV8396810
醋酸去氢表雄酮性质、用途与生产工艺
- 生物活性 Dehydroepiandrosterone 3-acetate 是雄性激素/雌性激素的前体物质,能够调节脊椎动物的攻击性行为。
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体内研究
Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.
- 用途 用于合成甾体激素药物
- 用途 醋酸去氢表雄酮是合成各种激素、计划生育用品等甾体激素类药物的重要中间体,由它可合成睾丸素、甲基睾丸素、雌二醇、雌三醇
- 更新日期:2024/11/11
- 产品编号:XW08532363
- 产品名称:醋酸去氢表雄酮 dehydroisoandrosterone 3-acetate;3β-acetoxy-5-androsten-17-one;3β-hydroxyandrost-5-en-17-one acetate;dehydroepiandrosterone 3-acetate;presterone acetate
- CAS编号:853-23-6
- 包装:100G
- 价格:659元
- 更新日期:2024/11/11
- 产品编号:XW08532362
- 产品名称:醋酸去氢表雄酮 dehydroisoandrosterone 3-acetate;3β-acetoxy-5-androsten-17-one;3β-hydroxyandrost-5-en-17-one acetate;dehydroepiandrosterone 3-acetate;presterone acetate
- CAS编号:853-23-6
- 包装:25G
- 价格:194元
- 公司名称:TOKYO CHEMICAL INDUSTRY CO., LTD.
- 联系电话:03-36680489
- 电子邮件:Sales-JP@TCIchemicals.com
- 国家:日本
- 产品数:28387
- 优势度:80
- 公司名称:WAKO
- 联系电话:--
- 电子邮件:labchem-tec@wako-chem.co.jp
- 国家:日本
- 产品数:6819
- 优势度:80