87686-36-0

Netzahualcoyone, the activity of netzahualcoyone on Bacillus subtilis and Escherichia coli was studied. The product inhibited the respiration of intact cells of B. subtilis but had no effect on the respiration of E. coli. However, when preparations of sonically disrupted cells were examined, inhibitory activity on both bacteria was observed.

Netzahualcoyone 是一种从植物科 Celastraceae 中分离出来的三萜类化合物。Netzahualcoyone 对革兰氏阳性细菌和酵母有广谱抗菌活性，但对革兰氏阴性细菌没有活性。Netzahualcoyone 可用于抗生素的开发和抗菌机制的研究。