57-94-3
中文名称
氯化筒箭毒碱
英文名称
D-TUBOCURARINE CHLORIDE
CAS
57-94-3
分子式
C37H41N2O6.ClH.Cl
分子量
681.65
MOL 文件
57-94-3.mol
结构式
基本信息
中文别名
氯化管箭毒碱
氯化筒箭毒碱
D-筒箭毒碱 氯化物
氯化D-筒箭毒碱
氯化箭毒块茎碱
氯化南美防已碱
氢氯化吐巴口拉令碱
D-氯化筒箭毒碱
氯化右旋筒箭毒
氯化竹筒箭毒素
氯筒箭毒碱
(+)-氯化筒箭毒碱
氯化筒箭毒碱
D-筒箭毒碱 氯化物
氯化D-筒箭毒碱
氯化箭毒块茎碱
氯化南美防已碱
氢氯化吐巴口拉令碱
D-氯化筒箭毒碱
氯化右旋筒箭毒
氯化竹筒箭毒素
氯筒箭毒碱
(+)-氯化筒箭毒碱
英文别名
7',12'-DIHYDROXY-6,6'-DIMETHOXY-2,2',2'-TRIMETHYLTUBOCURARANIUM CHLORIDE HCL
7',12'-DIHYDROXY-6,6'-DIMETHOXY-2,2'2'-TRIMETHYLTUBOCURARARIUM CHLORIDE
CURARE
D-TUBOCURARINE CHLORIDE
(+)-TUBOCURARINE CHLORIDE
TUBOCURARINE CHLORIDE
TUBOCURARINE CHLORIDE, D-
(+)-TUBOCURARINE DICHLORIDE
(+)-tubocurarinehydrochloride
amerizol
chloride,hydrochloride,(+)-tubocurarin
curarin-haf
d-7’,12’-dihydroxy-6,6’-dimethoxy-2,2’,2’-trimethyltubocuraraniumchloride
delacurarine
dextrotubocurarinechloride
dichloride,(+)-tubocurarin
d-paracurarinechloride
d-tubocurarinedichloride
d-tubocurarinehydrochloride
intocostrin
7',12'-DIHYDROXY-6,6'-DIMETHOXY-2,2'2'-TRIMETHYLTUBOCURARARIUM CHLORIDE
CURARE
D-TUBOCURARINE CHLORIDE
(+)-TUBOCURARINE CHLORIDE
TUBOCURARINE CHLORIDE
TUBOCURARINE CHLORIDE, D-
(+)-TUBOCURARINE DICHLORIDE
(+)-tubocurarinehydrochloride
amerizol
chloride,hydrochloride,(+)-tubocurarin
curarin-haf
d-7’,12’-dihydroxy-6,6’-dimethoxy-2,2’,2’-trimethyltubocuraraniumchloride
delacurarine
dextrotubocurarinechloride
dichloride,(+)-tubocurarin
d-paracurarinechloride
d-tubocurarinedichloride
d-tubocurarinehydrochloride
intocostrin
所属类别
原料药：骨骼肌松弛药
物理化学性质
| 外观性质 | 白色或微带黄色的六角形或五角形小片状结晶。 |
| 溶解性 | 溶于水。 |
| 熔点 | 274～275℃ |
| 比旋光度 | D20-25 +215° (c = 0.25-0.3 g/100 ml) |
| 密度 | 1.2074 (rough estimate) |
| 折射率 | 1.7350 (estimate) |
| 储存条件 | 2-8°C |
| 储存条件 | 2-8°C |
| 溶解度 | Soluble to 25 mM in water and to 10 mM in DMSO |
| 酸度系数(pKa) | pK: 7.4(at 25℃) |
| 形态 | 粉末 |
| 颜色 | white |
| 水溶解性 | Soluble to 25 mM in water |
| InChIKey | GXFZCDMWGMFGFL-KKXMJGKMSA-N |
| SMILES | [Cl-].[Cl-].[N+]1([C@@H]2Cc3cc(c(cc3)O)Oc4cc5c(cc4OC)CC[N+H]([C@H]5Cc6ccc(cc6)Oc7c2c(cc(c7O)OC)CC1)C)(C)C |
安全数据
| 危险性符号(GHS) |  GHS06 |
| 警示词 | 危险 |
| 危险性描述 | H300 |
| 防范说明 | P264-P270-P301+P310-P405-P501 |
| 危险品标志 | T |
| 危险类别码 | 25 |
| 安全说明 | 45 |
| 危险品运输编号 | UN 1544 6.1/PG 2 |
| 危险品运输编号 | UN 1544 6.1/PG 2 |
| WGK Germany | 3 |
| WGK Germany | 3 |
| RTECS号 | YO4900000 |
| 危险等级 | 6.1(b) |
| 包装类别 | III |
| 存储类别 | 6.1A - Combustible, acute toxic Cat. 1 and 2 very toxic hazardous materials |
| 危险性类别 | Acute Tox. 2 Oral |
| 毒性 | LD50 in mice, rats (mg/kg): 33.2, 27.8 orally in DMSO; 59.5, 36.9 orally in water (Rosen) |