57-42-1
中文名称
哌替啶
英文名称
MEPERIDINE
CAS
57-42-1
分子式
C15H21NO2
分子量
247.33
MOL 文件
57-42-1.mol
结构式
基本信息
中文别名
哌替啶
利多尔
杜冷丁
地露美
得美樂
哌替啶 溶液
甲醇(哌替啶)
利多尔
杜冷丁
地露美
得美樂
哌替啶 溶液
甲醇(哌替啶)
英文别名
Lydol
C07128
Dolsin
Nemerol
Demarol
Demerol
Petantin
Pethanol
Pethidin
Petydyna
C07128
Dolsin
Nemerol
Demarol
Demerol
Petantin
Pethanol
Pethidin
Petydyna
所属类别
原料药：镇痛药
物理化学性质
| 熔点 | 270°C |
| 沸点 | 390.37°C (rough estimate) |
| 密度 | 1.0267 (rough estimate) |
| 折射率 | 1.5130 (estimate) |
| 闪点 | 11 °C |
| 储存条件 | −20°C |
| 酸度系数(pKa) | pKa 8.7 (Uncertain) |
| 水溶解性 | 6.55g/L(25 ºC) |
| BCS Class | 1 |
| EPA化学物质信息 | 4-Piperidinecarboxylic acid, 1-methyl-4-phenyl-, ethyl ester (57-42-1) |
安全数据
| 危险性符号(GHS) |    GHS02,GHS06,GHS08 |
| 警示词 | 危险 |
| 危险性描述 | H225-H301+H311+H331-H370 |
| 防范说明 | P210-P260-P280-P301+P310-P311 |
| 危险品标志 | F,T |
| 危险类别码 | 11-23/24/25-39/23/24/25 |
| 安全说明 | 7-16-36/37-45 |
| 危险品运输编号 | UN 1230 3/PG 2 |
| WGK Germany | 1 |
| REACH 注册登记 | Active |
| 毒害物质数据 | 57-42-1(Hazardous Substances Data) |
| 毒性 | A narcotic analgesic used for moderate to severe pain and during obstetrical anesthesia. Its oral LD50 in rats is 170 mg/kg. It has multiple actions qualitatively similar to those of morphine, and therapy is similar to that for morphine. Advantages over morphine concerning efficacy and reduced risk of addiction were largely illusory. This, and potential drug interactions, have resulted in a dramatic reduction in use. |