57-37-4
基本信息
苯羟乙胺盐酸盐
胃乐康
乙胺痉平
盐酸贝那替秦
盐酸苯那辛
盐酸贝那替嗪
盐酸苯乃嗪
2-DIETHYLAMINOETHYL DIPHENYLGLYCOLATE HYDROCHLORIDE
BENACTIZINE HCL
BENACTYZINE HYDROCHLORIDE
BENZILIC ACID 2-(DIETHYLAMINO)ETHYL ESTER HYDROCHLORIDE
BENZILIC ACID DIETHYLAMINOETHYL ESTER HYDROCHLORIDE
LABOTEST-BB LT00159462
2-(diethylamino)-ethanobenzilatehydrochloride
2-(difenyl-hydroxyacetoxy)ethyl-diethylammoniumchlorid
2-diethylaminoethylesterkyselinybenzilovehydrochlorid
aktozin
amisyl
amitakon
amizil
arkadin
ay-5406
ay5406-1
benactyzinechloride
benaktin
benzeneaceticacid,alpha-hydroxy-alpha-phenyl-,2-(diethylamino)ethylester,
物理化学性质
| 外观性状 | 白色或几乎白色结晶性粉末。熔点177-181℃。25℃时100ml水中可溶解该品14.9g，几乎不溶于乙醚。无臭，味微苦。其碱基（[302-40-9]）熔点51℃。 |
| 熔点 | 177-179 °C(lit.) |
| 储存条件 | Keep in dark place,Sealed in dry,Room Temperature |
| 溶解度 | DMSO（微溶，加热）、甲醇（微溶） |
| 形态 | 固体 |
| 颜色 | Crystals from Me2CO |
| Merck | 1029 |
| CAS 数据库 | 57-37-4(CAS DataBase Reference) |
| EPA化学物质信息 | Benzeneacetic acid, .alpha.-hydroxy-.alpha.-phenyl-, 2-(diethylamino)ethyl ester, hydrochloride (57-37-4) |
安全数据
| 危险性符号(GHS) |  GHS06 |
| 警示词 | 危险 |
| 危险性描述 | H301 |
| 防范说明 | P264-P270-P301+P310+P330-P405-P501 |
| 危险品标志 | T |
| 危险类别码 | R23/24/25 |
| 安全说明 | S36/37/39-S45 |
| 危险品运输编号 | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS号 | DD2800000 |
| 海关编码 | 2922.50.4000 |
| 危险等级 | 6.1(b) |
| 包装类别 | III |
| 毒性 | LD50 orl-rat: 184 mg/kg TXAPA9 1,42,59 |
应用领域
制备方法
57-37-4(安全特性,毒性,储运)
图谱信息
乙胺痉平(57-37-4)质谱(MS)乙胺痉平(57-37-4)核磁图(1HNMR)乙胺痉平(57-37-4)核磁图(13CNMR)乙胺痉平(57-37-4)红外图谱(IR1)乙胺痉平(57-37-4)红外图谱(IR2)乙胺痉平(57-37-4)Raman光谱知名试剂公司产品信息
Benactyzine Hydrochloride,>98.0%(T)(57-37-4) TCI Shanghai
乙胺痉平价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/11/08 | HY-B1542A | 乙胺痉平 Benactyzine hydrochloride | 57-37-4 | 100mg | 500元 |
| 2024/11/08 | HY-B1542A | 乙胺痉平 Benactyzine hydrochloride | 57-37-4 | 10mM * 1mLin DMSO | 550元 |
| 2024/11/08 | B0053 | 盐酸贝那替嗪 Benactyzine Hydrochloride | 57-37-4 | 5G | 150元 |
常见问题列表
| Target | Value |
|
Muscarinic receptor
() |
Benactyzine hydrochloride and drofenine are widely used anticholinergic drugs which are also competitive inhibitors of BChE with K i values of 0.010±0.001 and 0.003±0.000 mM, respectively. Results indicate that the inhibition of BChE by Benactyzine hydrochloride is pure or partial competitive. Pure competitive inhibition can be distinguished from partial competitive inhibition by plotting v vs [Benactyzine] at a fixed [BTCh].
Benactyzine hydrochloride (1 mg/kg) does not influence the attention response. Benactyzine hydrochloride increases the duration of the exploratory-motor reaction, but slightly diminishes the salivation elicited by acetylcholine. There is no blocking effect of Benactyzine hydrochloride and promazine on the EEG-seizure activity elicited by acetylcholine, and almost no inhibitory effect on emotional reactions. Emotional reactions are blocked by high doses of imipramine and promazine, but not by Benactyzine hydrochloride. The data indicates that imipramine, promazine and Benactyzine hydrochloride influence the autonomic effects of serotonin in different ways. Promazine, and especially Benactyzine hydrochloride, inhibit and shorten the period of salivation elicited by the intra-amygdaloid injection of serotonin.