42079-78-7
基本信息
5-甲氧基黄酮,97%
METHOXYFLAVONE, 5-
5-methoxy-2-phenyl-4-benzopyrone
5-Methoxyflavone,97%
5-Methoxy-2-phenyl-4H-1-benzopyran-4-one
物理化学性质
| 熔点 | 131-133°C |
| 沸点 | 422.5±45.0 °C(Predicted) |
| 密度 | 1,155g/cm |
| 折射率 | 1,548 |
| 储存条件 | -20°C储存 |
| 溶解度 | 溶于甲醇 |
| 形态 | 粉末晶体 |
| 颜色 | 白色到近乎白色 |
| LogP | 3.470 (est) |
| CAS 数据库 | 42079-78-7(CAS DataBase Reference) |
安全数据
| 危险性符号(GHS) |  GHS07 |
| 警示词 | 警告 |
| 危险性描述 | H315-H319-H335 |
| 防范说明 | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| 危险品标志 | Xi |
| 危险类别码 | R36/37/38 |
| 安全说明 | S26-S36/37/39 |
| WGK Germany | 3 |
| 海关编码 | 2932.99.7000 |
知名试剂公司产品信息
5-Methoxyflavone, 97%(42079-78-7) Alfa Aesar
5-甲氧基黄酮价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-107790 | 5-甲氧基黄酮 5-Methoxyflavone | 42079-78-7 | 25mg | 500元 |
| 2024/01/25 | HY-107790 | 5-甲氧基黄酮 5-Methoxyflavone | 42079-78-7 | 10mM * 1mLin DMSO | 550元 |
| 2024/01/16 | B23700 | 5-甲氧基黄酮, 97% 5-Methoxyflavone, 97% | 42079-78-7 | 0.1g | 169元 |
常见问题列表
| Target | Value |
|
DNA polymerase β
() |
5-Methoxyflavone (compound 1) is identified as a candidate compound endowed with the ability to inhibit DNA pol-β in multiple and to prevent cell-cycle initiation and subsequent neuronal apoptosis in Aβ-challenged primary neuronal cultures. 5-methoxyflavone (10-30 μM) is able to significantly enhance toxicity of MMS on 92TAg cells. 5-Methoxyflavone (1 or 10 μM) significantly reduces polymerase activity on a gapped substrate.
5-Methoxyflavone (5-MF, 0-100 μg/mL) results in a time dependent reduction in the levels of antiapoptotic proteins cFLIP, Mcl-1 and an increase in the proapoptotic protein BAX. 5-MF induces both TRAIL-R1(DR4) and TRAIL-R2 (DR5) in a time-dependent manner.
5-Methoxyflavone (100, 150 mg/kg, i.p) significantly decreases the latency time to loss of righting reflex. 5-Methoxyflavone (50, 100 and 150 mg/kg, i.p) exhibits a significant and dose-dependent reduction in the spontaneous locomotor activity. 5-Methoxyflavone (50, 100 mg/kg, i.p) reduces the rearing response. 5-Methoxyflavone (100, 125 and 150 mg/kg, i.p) completely abolishesed the grooming response similar to diazepam treated animals.