3347-22-6
基本信息
二氰蒽醌
二噻农
2,3-二腈基-1,4-二硫代蒽醌
5,10-二氢-5,10-二氧萘基[2,3-B]-1,4-二硫杂环-2,3-二腈
75%二氰蒽醌可湿性粉剂
二氰蒽醌悬浮剂
2,3-DICYANO-1,4-DITHIAANTRAQUINONE
5,10-DIHYDRO-5,10-DIOXONAPHTHO-[2,3-B]-1,4-DITHIIN-2,3-DICARBONITRILE
5,10-DIHYDRO-5,10-DIOXONAPHTHO[2,3-B]-P-DITHIIN-2,3-DICARBONITRILE
5,10-DIOXO-5,10-DIHYDRO-NAPHTHO[2,3-B][1,4]DITHIINE-2,3-DICARBONITRILE
AKOS NCG1-0094
AKTUAN
CLUSTER
DELAN
DELAN-COL
DELAN(R)
Dicyano-1,4-dithia-anthraquinone
dithiaanthraquinone-2,3-dinitrile
DITHIANON
1,4-dithiaanthraquinone-2,3-dicarbonitrile
1,4-dithiaanthraquinone-2,3-dinitrile
2,3-dicarbonitrilo-1,4-diathiaanthrachinon
2,3-dinitrilo-1,4-dithia-9,10-anthraquinone
2,3-dinitrilo-1,4-dithiaanthraquinone
2,3-dinitrilo-1,4-dithia-anthraquinone
物理化学性质
| 外观性质 | 褐色结晶。 |
| 溶解性 | 微溶于水，溶于二噁烷、氯苯、氯仿。 |
| 熔点 | 225° |
| 沸点 | 402.1±45.0 °C(Predicted) |
| 密度 | d18 1.55 |
| 折射率 | 1.6360 (estimate) |
| 储存条件 | 0-6°C |
| 形态 | neat |
| 水溶解性 | 0.5mg/L(temperature not stated) |
| Merck | 13,3404 |
| BRN | 1325563 |
| LogP | 2.840 |
| CAS 数据库 | 3347-22-6(CAS DataBase Reference) |
| NIST化学物质信息 | Dithianone(3347-22-6) |
| EPA化学物质信息 | Naphtho[2,3-b]-1, 4-dithiin-2,3-dicarbonitrile, 5,10-dihydro-5,10-dioxo-(3347-22-6) |
安全数据
| 危险性符号(GHS) |    GHS05,GHS06,GHS09 |
| 警示词 | 危险 |
| 危险性描述 | H302-H317-H318-H330-H410 |
| 防范说明 | P273-P280-P301+P312+P330-P302+P352-P304+P340+P310-P305+P351+P338+P310 |
| 危险品标志 | Xn;N,N,Xn |
| 危险类别码 | R22-R50/53 |
| 安全说明 | S24-S60-S61 |
| 危险品运输编号 | UN 3077 |
| WGK Germany | 3 |
| RTECS号 | QL0700000 |
| 危险等级 | 6.1(b) |
| 包装类别 | III |
| 海关编码 | 29349990 |
| 毒害物质数据 | 3347-22-6(Hazardous Substances Data) |
| 毒性 | LD50 orally in rats, guinea pigs: 638, 110 mg/kg (Amadori, Heupt) |
常见问题列表
Reactive oxygen species (ROS)
Colletotrichum sp.
;
Elsinoe ampelina
;
Plasmopara viticola
;
Phomopsis viticola
When exponentially aerobic growing cells of
S. cerevisiae
are submitted to acute Dithianon treatment they loss cell wall and membrane integrity, dying by necrosis, and this behavior is associated to a depletion of reduced proteic and non-proteic thiol groups. An important increase of cellular reactive oxygen species (ROS) associated to mitochondrial membrane potential modifications on Dithianon treated cells are also detected.
In filamentous fungus, Dithianon inhibits mycelial growth and conidial germination. Studies on Ehrlich ascites carcinoma and yeast cells showed that Dithianon inhibits respiration and fermentation affecting several thiol enzymes of the glycolytic pathway as hexokinase, phosphofructokinase, and glyceraldeyde-3-phosphate dehydrogenase.
Dithianon has in vitro cytotoxic effect and affect cell transforming activity of BLAB/c 3 T3 cells.
The activity of testosterone hydroxylase of liver microsomes derived from male mice is increased when they are treated with acute doses of Dithianon, while in females an inactivating effect is observed.