18422-05-4
基本信息
腺苷-5'-磷酸
腺苷-5'-单磷酸一水合物
腺苷-5'-磷酸(一水)
5-ADENYLIC ACID
5'-AMP H2O
5'-AMP MONOHYDRATE
A-5'-P
ADENOSINE 5'-MONOPHOSPHATE
ADENOSINE 5'-MONOPHOSPHATE MONOHYDRATE
ADENOSINE 5'-MONOPHOSPHORIC ACID MONOHYDRATE
ADENYLIC ACID MONOHYDRATE
AMP
ADENOSINE 5'-MONOPHOSPHATE FREE ACID97+% FROM YEAS
5'-AMP=Adenylicacid
ADENOSINE-5'-MONOPHOSPHATE 1-HYDRATE
5-Adenylic acid, monohydrate
Adenosine-5''-monophosphoric acid (and/or unspecified salts)
5'-AMP
Adenosine-5'-monophosphoric acid monohydrate >96%
AMP monohydrate
5μ-AMP, Adenylic acid from muscle, AMP
5μ-Adenylic acid, 5μ-AMP, A-5μ-P, AMP
物理化学性质
| 熔点 | 183-188 °C (dec.)(lit.) |
| 比旋光度 | -48 º (c=2% in 2% NaOH) |
| FEMA | 4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE |
| 储存条件 | 2-8°C |
| 溶解度 | H2O: with addition of mild alkalisoluble |
| 形态 | 固体 |
| 颜色 | 白色至灰白色 |
| Merck | 14,158 |
| BRN | 5205540 |
| CAS 数据库 | 18422-05-4(CAS DataBase Reference) |
安全数据
| 危险性符号(GHS) |  GHS07 |
| 警示词 | 警告 |
| 危险性描述 | H302-H315-H319-H335 |
| 防范说明 | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
| 危险品标志 | Xi |
| 危险类别码 | 36/37/38 |
| 安全说明 | 26-36 |
| WGK Germany | 3 |
| RTECS号 | AU7480500 |
| F | 8-10-21 |
| TSCA | Yes |
| 海关编码 | 2934999090 |
应用领域
常见问题列表
Adenosine A 1 receptor
Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate (5′-AMP)-induced cell toxicity is negligible at concentrations of 25 to 400 μM in RAW264.7 cells. Adenosine 5'-monophosphate monohydrate significantly attenuates the mRNA expression of tumor necrosis factor-α (TNF-α) and interleukin (IL)-6 in RAW264.7 cells. The dose-dependence of TNF-α and IL-6 mRNA show that at concentration of 400 μM, Adenosine 5'-monophosphate monohydrate exhibits the maximum inhibition. Exposure of cells to Adenosine 5'-monophosphate monohydrate significantly reduces recruitment of NF-κB p65 to TNF-α, IL-6, and IL-1β gene promoters.
C57BL/6J mice treated with Adenosine 5'-monophosphate monohydrate (5′-AMP) markedly increases hepatic adenosine level. Survival rate in PBS-treated mice (n=15) is 60% (8 h) and 33.3% (24 h), whereas survival rate in Adenosine 5'-monophosphate monohydrate-treated mice (n=15) is 100% (8 h) and 93.3% (24 h). Serum aspartate transaminase (AST) and alanine transaminase (ALT) levels are significantly lowered in the Adenosine 5'-monophosphate monohydrate group than in the vehicle group. The area and extent of necrosis is attenuated and the infiltration of inflammatory cells is reduced in the Adenosine 5'-monophosphate monohydrate group.
图谱信息
腺苷-5'-单磷酸一水合物(18422-05-4)核磁图(1HNMR)腺苷-5'-单磷酸一水合物(18422-05-4)红外图谱(IR)腺苷-5'-单磷酸一水合物(18422-05-4)Raman光谱知名试剂公司产品信息
腺苷-5'-单磷酸一水合物价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-A0181A | 腺苷-5'-单磷酸一水合物 Adenosine 5'-monophosphate monohydrate | 18422-05-4 | 500mg | 400元 |
| 2024/01/25 | HY-A0181A | 腺苷-5'-单磷酸一水合物 Adenosine 5'-monophosphate monohydrate | 18422-05-4 | 10mM * 1mLin Water | 500元 |
| 2024/01/25 | HY-A0181A | 腺苷-5'-单磷酸一水合物 Adenosine 5'-monophosphate monohydrate | 18422-05-4 | 1g | 500元 |