1355446-05-7
英文名称
ML309
CAS
1355446-05-7
分子式
C29H29FN4O2
分子量
484.56
MOL 文件
1355446-05-7.mol
结构式
基本信息
英文别名
ML309
应用领域
用途一
ML309 is a potent inhibitor of R132H mutant IDH1 capable of reducing 2-hydroxyglutarate production in U87 MG glioblastoma cells. ML309 is capable of potent and selective inhibition of mutant IDH1 and effectively lowers cell-based production of 2-HG in a U87MG mutant glioblastoma cell line.